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Applications of MALDI-TOF MS in environmental microbiology
The Analyst, 2016Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) is an emerging technique for microbial identification, characterization, and typing.
Inês C. Santos +2 more
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MALDI-TOF-MS Analysis of Protein and DNA
The Neuroscientist, 2001Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) has become a powerful and widespread analytical tool in all fields of life science. The wide mass range (1-300 kDa), high accuracy, and sensitivity make it a superior method for analysis of all kinds of biomolecules including proteins, nucleic acids, and ...
T, Bonk, A, Humeny
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Biomarker Characterization by MALDI–TOF/MS
2015Mass spectrometric techniques frequently used in clinical diagnosis, such as gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, ambient ionization mass spectrometry, and matrix-assisted laser desorption ionization/time-of-flight mass spectrometry (MALDI-TOF/MS), are discussed.
Yi-Tzu, Cho +6 more
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The application of MALDI TOF MS in biopharmaceutical research
International Journal of Pharmaceutics, 2011The development and quality assessment of modern biopharmaceuticals, particularly protein and peptide drugs, requires an array of analytical techniques to assess the integrity of the bioactive molecule during formulation and administration. Mass spectrometry is one of these methods and is particularly suitable for determining chemical modifications of ...
Alexandra P, Kafka +3 more
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MALDI-TOF MS analysis of plant proanthocyanidins
Journal of Pharmaceutical and Biomedical Analysis, 2010Proanthocyanidins or condensed tannins are among the most abundant polyphenols compounds in our diet and may play a key role in the prevention of cardiovascular and neurodegenerative diseases and cancer. These antioxidants are widely distributed in the plant kingdom both in food plants and in non-food plants.
Monagas Juan, María Josefina +4 more
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Challenges in biomarker discovery with MALDI-TOF MS
Clinica Chimica Acta, 2016MALDI-TOF MS technique is commonly used in system biology and clinical studies to search for new potential markers associated with pathological conditions. Despite numerous concerns regarding a sample preparation or processing of complex data, this strategy is still recognized as a popular tool and its awareness has risen in the proteomic community ...
Joanna, Hajduk +2 more
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Analysis of oligosaccharides in beer using MALDI-TOF-MS
Food Chemistry, 2012Oligosaccharides in four different brands of beer (Cass, Hite, Budweiser, Miller) were systematically analysed with three different dihydroxybenzoic acid (DHB) isomer matrices (2,4-DHB, 2,5-DHB, and 2,6-DHB) using matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF-MS).
Eunhye, Park +3 more
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Identification of Staphylococcus intermedius Group by MALDI-TOF MS
Systematic and Applied Microbiology, 2011The Staphylococcus intermedius Group includes S. intermedius, S. pseudintermedius and S. delphini, coagulase-positive bacteria commonly isolated from animals. The identification of organisms belonging to this group is presently carried out using molecular methods. This study assessed the suitability of MALDI-TOF MS for their identification.
Decristophoris, Paola +4 more
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Direct MALDI-TOF MS Identification of Bacterial Mixtures
Analytical Chemistry, 2018Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is now widely used to characterize bacterial samples for clinical diagnosis, food safety control, environmental monitoring, and so on. However, existing standard approaches are only applied to analyze single colonies purified by plate culture, which limits the ...
Yi Yang, Yu Lin, Liang Qiao
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Characterization of Oligo- and Polysialic Acids by MALDI-TOF-MS
Analytical Chemistry, 2007Oligo- and polysialic acids (oligo/polySia) are characterized by a high diversity in nature due to the different types of sialic acids linked to each other and glycosidic linkages involved. Considering the methods that are presently available for analysis of oligo/polySia chains, only fluorometric anion-exchange high-performance liquid chromatography ...
Sebastian P, Galuska +3 more
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