Results 61 to 70 of about 12,519,177 (391)
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti+10 more
wiley +1 more source
The Private Lands Opportunity: The Case for Conservation Incentives [PDF]
Outlines a number of opportunities available for enlisting the participation of landowners as partners in conservation as part of an effort to meet the nation's conservation ...
Michael Bean+3 more
core
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
The Professional Induction of Headteachers in England: Findings from the IBPS project [PDF]
This paper reports on the data gathered through a self-completion questionnaire administered to a sample of headteachers in England who took up post in September, 2000.
Male, T
core
Obesity impairs male fertility through long-term effects on spermatogenesis
Objective This study aimed to investigate the effect and possible underlying mechanisms of high-fat diet-induced obesity on spermatogenesis in male rats. Methods A total of 45 male rats were randomly divided into control (n = 15, normal diet) and obesity
Yan-Fei Jia+9 more
doaj +1 more source
Recent advances in understanding and managing male infertility
Infertility is a prevalent condition affecting an estimated 70 million people globally. The World Health Organization estimates that 9% of couples worldwide struggle with fertility issues and that male factor contributes to 50% of the issues.
J. Fainberg, J. Kashanian
semanticscholar +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
The Impact of National Culture on School Leadership in England [PDF]
This paper reports on the survey findings of an international project to examine the impact of national culture on school leadership. The survey instrument was based on the work of Geert Hofstede, with the data collected for this paper emerging from semi-
Male, T
core
The impact on a primary school community in England of failed inspection and subsequent academisation [PDF]
© 2015 Taylor & Francis. This research reports upon the impact of two concurrent processes of Special Measures and academisation applied to a primary school in the north of England as a result of an unsatisfactory inspection by the Office for Standards ...
Elton, J, Male, T
core +1 more source
Magnetic perforation: Why we say NO to kids
Foreign body (FB) ingestion is common among children. It is alarming when it is a magnetic foreign body as it can cause interloop attraction resulting in perforation, fistulas and or volvulus.
Aishath Azna Ali+9 more
doaj