Results 41 to 50 of about 396,577 (261)
SUMMARY Male breast cancer is a rare disease, often with a late presentation and poor prognosis. The mainstay of treatment is modified radical mastectomy, with axillary node dissection to assess stage, prognosis and the need for adjuvant treatment. When matched for age, tumour size, grade and axillary nodal status, the prognosis is similar for males ...
A S, Jepson, I S, Fentiman
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LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Background: Male breast lesions are uncommon but pose significant diagnostic challenges, particularly in resource-limited rural settings. Distinguishing benign conditions like gynecomastia from malignancies is crucial for appropriate management.
Ritu Roy +2 more
doaj +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Pictorial essay: Mammography of the male breast
Mammography is an imaging modality that is widely perceived to be of use only in women for the detection and diagnosis of breast pathologies. Here, we present a pictorial essay on the mammographic spectrum of male breast pathologies.
Popli Manju, Popli V, Bahl P, Solanki Y
doaj +3 more sources
A rare case of primary breast angiosarcoma in a male: a case report
Background Sarcomas account for less than 1% of primary breast cancers, and breast angiosarcomas are responsible for only 0.05% of all breast malignancies. The male breast has the same potential for malignant transformation as the female breast. However,
Benedito Borges da Silva +13 more
doaj +1 more source
The male breast is a non-functional and rudimentary organ, but similarly to the female breast, it can be affected by various diseases. In contrast to female breast cancer, male breast cancer has a low incidence, and there is no established breast ...
Hyun Kyung Jung, Yun-Jung Lim
doaj +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
The Prevalance of Male Breast Cancer and our Clinical Experiences
Aim: Male breast carcinomas are very rare tumors. In this study, we aimed to evaluate the male patients who were diagnosed with breast carcinoma and admitted to our outpatient clinic. Methods: Among 268 patients diagnosed with breast carcinoma in the
Cihad Tatar +2 more
doaj +1 more source
Male breast tuberculosis [PDF]
Summary Tuberculosis of the breast is rare and tuberculosis of the male breast is not a recognised entity. We describe a man with tuberculosis of the breast which was clinically thought to be a malignancy.
C, Jaideep, M, Kumar, A K, Khanna
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