Results 51 to 60 of about 3,727,561 (167)

MicroRNA‐130a‐3p Targets the Androgen‐Related Transcription Factor MAFB: Effects on Proliferation, Migration, Apoptosis, and Cell Cycle in Hypospadias

Pediatric Discovery, EarlyView.
MicroRNA‐130a‐3p targets and inhibits MAFB expression, leading to the development of hypospadimas. MicroRNA‐130a‐3p inhibits the expression of MAFB, disrupts the normal processes of cell proliferation, migration, cell apoptosis, and cycle progression, and ultimately leads to the development of hypospadias.
Jiaxin Zhou, Yixuan Wang, Zhicheng Zhang, Qiang Zhang, Zhenmin Liu, Hongsong Chen, Xingguo Luo, Chunlan Long, Lianju Shen, Xing Liu, Guanghui Wei   +10 more
wiley   +1 more source

Preoperative caudal blocks associated with decreased cumulative opioid requirements compared to postoperative caudal blocks in pediatric urologic surgery

UroPrecision, EarlyView.
Abstract Background Caudal blocks (CB) are a cornerstone of pediatric urologic surgery, providing effective analgesia while mitigating potential neurotoxicity associated with general anesthesia and opioids. However, the optimal timing of CB—preoperative versus postoperative—remains controversial.
Jordan L. Mendelson, William Brenseke, Diego Alvarez Vega, William Nguyen, Mohammed Shium, Saige Gitlin, Ronnie G. Fine, Steven C. Friedman, Mark Horowitz, Walter I. Weiss, Raghu Idupuganti, Jordan S. Gitlin   +11 more
wiley   +1 more source

Acceptability of a Pilot Intervention of Voluntary Medical Male Circumcision and HIV Education for Street-Connected Youth in Western Kenya.

Journal of Adolescent Health, 2019
PURPOSE Street-connected youth (SCY) in Kenya and elsewhere in sub-Saharan Africa are at high risk of HIV. Voluntary Male Medical Circumcision (VMMC) reduces the risk of female-to-male HIV transmission.
Mia Kibel, P. Shah, D. Ayuku, D. Makori, E. Kamaara, E. Choge, Joyce Nyairo, P. Abuya, M. Wahome, J. Wachira, P. Braitstein   +10 more
semanticscholar   +1 more source

Who Is a Patriotic Man? Rethinking Hegemonic Masculinity in Modern Iran

Gender &History, EarlyView.
ABSTRACT This article examines the analytical viability of the concept of “hegemonic masculinity” in the historical study of masculinities in early‐twentieth‐century Iran (c.1890–1941). It argues that a radical problematizing of the concepts of hegemony, class, “the West,” and patriotism helps us move beyond the binaries of Western‐Iranian and modern ...
Ali Hashemian
wiley   +1 more source

Early infant male circumcision: Systematic review, risk-benefit analysis, and progress in policy

World Journal of Clinical Pediatrics, 2017
AIM To determine whether recent evidence-based United States policies on male circumcision (MC) apply to comparable Anglophone countries, Australia and New Zealand.
B. Morris, S. Kennedy, A. Wodak, A. Mindel, D. Golovsky, L. Schrieber, E. Lumbers, David Handelsman, J. Ziegler   +8 more
semanticscholar   +1 more source

Multifactorial determinants of male genital measurements: Correlations of stretched penile length and anogenital distance with anthropometric parameters

Andrology, EarlyView.
Abstract Background The stretched penile length is recognized as the most reliable measure of true penile size, this fact is not widely acknowledged, and societal myths often associate penile length with other anthropometric measurements. While markers of prenatal androgen exposure, such as anogenital distance and the second‐to‐fourth digit ratio (2D ...
Coşkun Kaya, Mehmet Erhan Aydın, Aykut Aykaç, Sevda Sungur, Murat Dursun, Ateş Kadıoğlu   +5 more
wiley   +1 more source

Seventh Åland Island Meeting on von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The seventh Åland Island Meeting on von Willebrand Disease (VWD) was held on the Åland archipelago in Finland, from 26 to 28 September 2024. Aim The meeting brought together experts in the field of VWD from around the world to share the latest advances and knowledge in VWD.
Riitta Lassila, Ruben Bierings, Nathan T. Connell, Fernando F. Corrales‐Medina, Augusto B. Federici, Veronica H. Flood, Floor Heubel‐Moenen, Jill M. Johnsen, Geoffrey Kuppens, Davide Matino, Carolyn Millar, Ingmar Schoen, Anish Sharda, Robert F. Sidonio Jr, Alok Srivastava, Timea Szanto, Angela C. Weyand, Erik Berntorp   +17 more
wiley   +1 more source

ADVANTAGES AND DISADVANTAGES OF MALE CIRCUMCISION TECHNIQUES: A LITERATURE REVIEW

Jurnal Urologi Indonesia, 2021
Objective: To compare the advantages and disadvantages of male circumcision techniques. The articles of male circumcision techniques were investigated from October 2018 to December 2018 through Google Scholar and Proquest.
Andersen, Felicia Adelina Shannen, Ridwan Mataram   +2 more
doaj   +1 more source

Male genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas, Rory Barry, Richard E. Watchorn, Christopher B. Bunker   +3 more
wiley   +1 more source

Recurrent UTIs in Children With CAKUT

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital abnormalities of the kidney and urinary tract (CAKUT) encompass diverse diagnoses that commonly present as urinary tract dilatation and are the leading cause of kidney failure in children. Antenatal hydronephrosis occurs in ~1% of pregnancies; most resolve spontaneously, but conditions such as posterior urethral valves (PUV ...
Lucielle Standish, Holly Campbell, Shehryar Saharan, Lilian M. Johnstone, Neil Price, Chris Kimber, Kiarash Taghavi   +6 more
wiley   +1 more source