Results 291 to 300 of about 3,247,679 (362)

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt   +2 more
wiley   +1 more source

Elective Neck Dissection in cT1‐4 N0M0 Head and Neck Spindle Cell Carcinoma

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To investigate the survival benefit of elective neck dissection (END) over neck observation in surgically resected cT1‐4 N0M0 head and neck spindle cell carcinoma (HNSpCC). Study Design Retrospective cohort study. Setting The 2006 to 2018 hospital‐based National Cancer Database (NCDB).
Praneet C. Kaki   +5 more
wiley   +1 more source

Health Disparities in Rhinology—A Scoping Review

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective This scoping review aims to systematically evaluate the existing health disparities research in rhinology, identifying key themes, gaps, and opportunities for future investigation. Data Sources A systematic search of PubMed, Embase, and Web of Science was conducted using terms related to rhinology topics and health disparities as ...
Jaynelle Gao   +6 more
wiley   +1 more source

Novel Findings in Pediatric and Adolescent Patients With Cancer and a Germline SMARCA4 Variant

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction SMARCA4 is a known susceptibility gene for malignant rhabdoid tumors (MRT) in children and small cell carcinoma of the ovary hypercalcemic type (SCCOHT) in young females and women. Recently, a novel association between germline SMARCA4 variants and predisposition to neuroblastoma was proposed.
Nienke van Engelen   +12 more
wiley   +1 more source

Fetal Urinoma Secondary to Posterior Urethral Valve and Its Association to Postnatal Renal Function: A Multicenter Retrospective Study

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Aim The role of prenatal urinoma in lower urinary tract obstruction (LUTO) such as posterior urethral valves (PUV) is debated. We aimed to describe the risk factors associated with fetal urinoma and the association between fetal urinoma and postnatal renal function before 2 years of age.
Flore‐Anne Martin   +10 more
wiley   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada   +2 more
wiley   +1 more source

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