Results 1 to 10 of about 68,853 (181)
Best Practice & Research Clinical Obstetrics & Gynaecology, 2014 Clear evidence shows that many men and women would welcome new male methods of contraception, but none have become available. The hormonal approach is based on suppression of gonadotropins and thus of testicular function and spermatogenesis, and has been investigated for several decades.
Jing, Chao +2 more
+7 more sources
Endocrine Reviews, 2002 The provision of safe, effective contraception has been revolutionized in the past 40 yr following the development of synthetic steroids and the demonstration that administration of combinations of sex steroids can be used to suppress ovulation and, subsequently, other reproductive functions.
R A, Anderson, D T, Baird
+7 more sources
Tex13a Optimizes Sperm Motility via Its Potential Roles in mRNA Turnover
Frontiers in Cell and Developmental Biology, 2021 mRNAs have been found to undergo substantial selective degradation during the late stages of spermiogenesis. However, the mechanisms regulating this biological process are unknown. In this report, we have identified Tex13a, a spermatid-specific gene that
Yinchuan Li +10 more
doaj +1 more source
Frontiers in Immunology, 2022 Leydig cells (Lc), located in the interstitial space of the testis between seminiferous tubules, produce 95% of testosterone in male individuals, which is pivotal for male sexual differentiation, spermatogenesis, and maintenance of the male secondary sex
Yinchuan Li +10 more
doaj +1 more source
Frontiers in Physiology, 2022 In mammalian cells, 10 different adenylyl cyclases produce the ubiquitous second messenger, cyclic adenosine monophosphate (cAMP). Amongst these cAMP-generating enzymes, bicarbonate (HCO3−)-regulated soluble adenylyl cyclase (sAC; ADCY10) is uniquely ...
Thomas Rossetti +8 more
doaj +1 more source
Ethnomedicine Study on Justicia gendarussa for Male Contraception at the Nimboran Ethnic, Jayapura
Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2022 Background: Justicia gendarussa from Papua has traditionally been used for the treatment of several diseases, and phytochemical studies have been carried out since 1987.
Niluh Indrawati +3 more
doaj +1 more source
Contraception and Reproductive Medicine, 2023 Background There is high global demand for new methods of male birth control (MBC). However, contemporary evidence regarding men’s method-specific attitudes and their determinants is sparse.
Summer L. Martins, Christy M. Boraas
doaj +1 more source
Fertility and Sterility, 2016 AbstractApproximately 40 to 50% of pregnancies are unintended. Contraceptive use significantly reduces the risk of unintended pregnancy. Approximately 70% of couples' contraceptive use is female and 30% is male, attributable to the reliance on condoms and vasectomies.
openaire +4 more sources
Frontiers in Cell and Developmental Biology, 2023 The exclusive expression of CatSper in sperm and its critical role in sperm function makes this channel an attractive target for contraception. The strategy of blocking CatSper as a male, non-hormonal contraceptive has not been fully explored due to the ...
Guillermina M. Luque +9 more
doaj +1 more source
An examination of the barriers to and benefits from collaborative couple contraceptive use in Rwanda
Reproductive Health, 2021 Background Supportive male involvement is strongly correlated with contraceptive use. In Rwanda, where the contraceptive prevalence rate among married women increased from 17 to 52% from 2005 to 2010, and stagnated at 53% in 2015, understanding the role ...
Hilary Schwandt +25 more
doaj +1 more source