Results 201 to 210 of about 105,857 (310)

Strategies to Manage Dosing Deviations and Interruptions of Cabotegravir Long‐Acting Intramuscular Injections

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Long‐acting cabotegravir is approved for HIV treatment and prevention. To guide management of dosing deviations and interruptions, concentration‐time profiles for monthly and every 2 months regimens were simulated using a population pharmacokinetic (PPK) model.
Kelong Han, Ronald D. D'Amico, William R. Spreen, Susan L. Ford   +3 more
wiley   +1 more source

The role of the World Health Organization in male contraceptive development [PDF]

Nancy Kidula, Brian T. Nguyen, Ndema Habib, Mario Festin, Igor Toskin, James Kiarie   +5 more
openalex   +1 more source

A Phase 1 Open‐Label Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Single Intranasal Dose of Zavegepant in Healthy Chinese Adults

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Zavegepant is the only calcitonin gene‐related peptide antagonist approved as a nasal spray in the United States for acute treatment of migraine in adults with or without aura. This Phase 1, open‐label study evaluated the pharmacokinetics, safety, and tolerability of a single intranasal dose of zavegepant 10 mg in 12 healthy Chinese adults ...
Qiong Wei, Jufang Wu, Yangyi Dai, Jiaye Lin, Beikang Ge, Yanhui Sun, Jing Zhang, Jing Wang, Chen Li, Ding Ding, Jing Liu, Mohamed H. Shahin   +11 more
wiley   +1 more source

Assessing safety in hormonal male contraception: a critical appraisal of adverse events reported in a male contraceptive trial. [PDF]

BMJ Sex Reprod Health, 2020
Abbe C, Roxby AC.
europepmc   +1 more source

Las chicas sólo quieren divertirse? Sexualidad, embarazo y maternidad en las adolecentes de Bolivia [PDF]

Este estudio busca cuantificar actividad sexual, embarazo y maternidad adolescente en Bolivia utilizando la Encuesta de Demografía y Salud más reciente. Los resultados descriptivos sugieren que la actividad sexual, el embarazo y la maternidad adolescente
Mariana Alfonso
core  

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, EarlyView.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

Kinetics of the inhibition and recovery of spermatogenesis induced by treatment with WIN 18,446, a male contraceptive, in mice. [PDF]

Andrology
Paik J, Snyder JM, Kim A, Haenisch M, Fogassy K, Amory JK.   +5 more
europepmc   +1 more source

The relationship of male condoms and withdrawal contraceptive methods with female sexual function and satisfaction: a cross sectional study

, 2016
Mitra Tadayon, Maryam Honarjoo, Zahra Abbaspoor   +2 more
openalex   +2 more sources

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali, Stephan van Erp, Cornelis Kramers, Cornelis J. Tack, Bastiaan E. de Galan   +4 more
wiley   +1 more source

Effect of hydro-ethanol extract of Caesalpinia pulcherrima (L.) Sw. leaves in human and rat: In vitro approach of male contraceptive development. [PDF]

JBRA Assist Reprod
Lohar P, Pal D, Mondal T, Das P, Ghosh D.   +4 more
europepmc   +1 more source