Results 101 to 110 of about 1,998,905 (287)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Negotiations of minority ethnic rugby league players in the Cathar country of France [PDF]

, 2008
This article is based on new empirical, qualitative research with minority ethnic rugby league players in the southwest of France. Drawing on similar research on rugby league in the north and the south of England, the article examines how rugby league ...
Anderson, B., Anthias, F., Augustin, J.P., Brah, A., Bromberger, C., Bulmer, M., Burdsey, D., Cliff Spracklen, Collins, T., Connell, R., Dauncey, H., Dine, P., Edwards, T., Hylton, K., Karl Spracklen, Long, J., Maffesoli, M., Mignon, P., Noiriel, G., Pociello, C., Pringle, R., Rylance, M., Schofield, G., Silverstein, P., Spracklen, K., Terret, T., Ungar, S., Wievorka, M.   +27 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

A descriptive study on demographic and behavioral characteristics of males and their responses to a male involvement intervention in Blantyre, Malawi

The Pan African Medical Journal, 2016
INTRODUCTION: male involvement (MI) remains a key factor in the enrollment and retention of pregnant women in the Prevention of Mother to child transmission (PMTCT) of Human Immunodeficiency Virus (HIV) services.
Alinane Linda Nyondo-Mipando, Angela Faith Chimwaza, Adamson Sinjani Muula   +2 more
doaj   +1 more source

A Qualitative Study on Men’s Involvement in Reproductive Health of Women among Auto-rickshaw Drivers in Bangalore Rural [PDF]

, 2012
Background: Men’s reproductive health directly affects the partner’s reproductive health. Men also may serve as gatekeepers to women’s access to reproductive health services. “Male involvement” in reproductive health and family planning programmes is not
Gaikwad, VS, Murthy, TSM, Sudeepa, D
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Male infertility-related molecules involved in sperm-oocyte fusion

Journal of Reproduction and Development, 2017
Male infertility has become a very serious problem in the human reproduction system, but the molecular mechanism of infertility remains largely unknown. Fertilization is the phenomenon in which a sperm and oocyte find each other, interact, and fuse. Sperm-oocyte fusion-related factors on the sperm side play crucial roles in male infertility.
Mou, Lisha, Xie, Ni
openaire   +4 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Determinants of Male Partner Involvement in Utilization of Family Planning Methods: A Mixed Methods Study

Journal of Integrated Health Sciences
Introduction: Despite many efforts to promote gender equality in reproductive health, there has been minimal progress in reducing the gap between men’s and women’s contraceptive utilization.
Pushpa Omprakash Lokare, Ajinkya Deshmukh, Amruta Bavadekar, Vinod Deorao Karanjekar, Sanjeev Mohan Chaudhary   +4 more
doaj   +1 more source

The politics of space involving male heterosexuality

Japanese Journal of Human Geography, 2002
The politics of space involving sexuality has been studied mainly from the perspective of women and of homosexual men. Women's studies of space make clear that space is not constructed for female sexuality but for that of males. Gay studies of space conclude that, though homosexual men are 'male', they are inclined to be alienated from spaces which are
openaire   +2 more sources