Results 111 to 120 of about 1,998,905 (287)

Student-adult mentoring relationships : experiences from a Scottish school-based programme [PDF]

open access: yes, 2014
The project on which this paper is based was funded by the Academy for Educational Development (AED), now incorporated as part of the FHI Development 360 LLC (FHI 360) in Washington, DC, USA.Peer ...
Mtika, Peter, Payne, Frances
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Involvement of ALF in human spermatogenesis and male infertility

open access: yesInternational Journal of Molecular Medicine, 2006
We conducted this study to explore functions of TF II Aalpha/beta-like factor (ALF) during human spermatogenesis, and the relationship of its expression levels with male infertility. The RT-PCR and Western blot analyses illustrated that ALF was highly expressed in adult testis.
Min, Huang   +6 more
openaire   +3 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Social and cultural barriers to husbands' involvement in maternal health in rural, Gambia

open access: yesThe Pan African Medical Journal, 2017
INTRODUCTION: While many studies have documented a number of socio-cultural barriers to male involvement in maternal health, in The Gambia very little information is known about the social and cultural practices that characterized male involvement in ...
Mat Lowe
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Factors Associated with Male Involvement in Institutional Child Delivery Services of Their Partner in Southern Ethiopia

open access: yesNursing: Research and Reviews, 2023
Meseret Alemu,1 Girmay Adhena,2 Nega Assefa,3 Yadeta Dessie3 1Department of Reproductive Health, Lemmo District Health Office, Hossana, Southern Ethiopia; 2Department of Reproductive Health, International Medical Corps, Gambella, Ethiopia; 3School of ...
Alemu M, Adhena G, Assefa N, Dessie Y
doaj  

Predictors of discordance among Chilean families [PDF]

open access: yes, 2012
Parent-youth agreement on parental behaviors can characterize effective parenting. Although discordance in families may be developmentally salient and harmful to youth outcomes, predictors of discordance have been understudied, and existing research in
Castillo, M.   +5 more
core  

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