Results 211 to 220 of about 451,113 (281)

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

open access: yesAdvanced Science, EarlyView.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu   +23 more
wiley   +1 more source

Impact of a Rapid Results Initiative Approach on Improving Male Partner Involvement in Prevention of Mother to Child Transmission of HIV in Western Kenya. [PDF]

open access: yesAIDS Behav, 2018
Akama E   +13 more
europepmc   +1 more source

Involvement of Male Partners: An Important Step towards Solving Nutritional Anemia

open access: yesJournal of South Asian Federation of Obstetrics and Gynaecology
Madhva Prasad   +4 more
openaire   +1 more source

Inhibiting cGAS‐STING to Preserve Mitochondrial–Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age‐Related Tendinopathy

open access: yesAdvanced Science, EarlyView.
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang   +11 more
wiley   +1 more source

Mindfulness for people with long-term conditions and their family caregivers: a systematic review [PDF]

open access: yes, 2019
Atteih   +71 more
core   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

open access: yesAdvanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun   +5 more
wiley   +1 more source

'He's not my pimp': toward an understanding of intimate male partner involvement in female sex work at the Mexico-US border. [PDF]

open access: yesCult Health Sex, 2018
Mittal ML   +6 more
europepmc   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

open access: yesAdvanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu   +15 more
wiley   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

open access: yesAdvanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han   +10 more
wiley   +1 more source

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