Results 121 to 130 of about 3,981,898 (220)
NHS Evidence - kidney diseases and male urogenital disorders is one of 34 online specialist collections provided by the National Institute for Health and Clinical Excellence (NICE). This particular specialist collection is managed by a team from Oxford University Health Care Libraries.
openaire +1 more source
Broadening horizons: Pathogenesis and therapeutics of renal ciliopathies
This review elucidates the molecular mechanisms and aberrant signaling pathways in renal ciliopathies, links genetic heterogeneity to clinical phenotypes, and lays a theoretical basis for prenatal diagnosis and novel therapies. Abstract Renal ciliopathies encompass a spectrum of genetic disorders arising from structural or functional impairments of ...
Qiaowei Zhang +7 more
wiley +1 more source
Circular RNAs (circRNAs) are stable, stage‐ and tissue‐specific regulators of gene expression warranting their study in abnormal fetal lung development in congenital diaphragmatic hernia (CDH). We present a CDH‐specific circRNA biosignature in the nitrofen rat model (E15/E21) using orthogonal validation with human comparison and discovered conserved ...
Marietta Jank +16 more
wiley +1 more source
Type 5 Diabetes Mellitus: Pathophysiology, Clinical Phenotype, and Nutritional Management
ABSTRACT Type 5 Diabetes Mellitus (T5DM) is an emerging diabetes phenotype linked to chronic undernutrition. It predominantly affects young, lean individuals in low‐ and middle‐income countries. After its formal recognition by the International Diabetes Federation in 2025, T5DM resurfaced as a clinically relevant insulin‐deficient phenotype.
İrem Nur Şahin Anılgan +1 more
wiley +1 more source
Unveiling the Role of Human Papillomavirus in Urogenital Carcinogenesis a Comprehensive Review
Human papillomavirus (HPV), an oncogenic DNA virus, is the most common sexually transmitted virus and significant public health concern globally. Despite the substantial prevalence of HPV infection among men, routine testing remains elusive due to the ...
Beliz Bahar Karaoğlan, Yüksel Ürün
core +1 more source
Head and Neck Metastases From Infraclavicular Primary Tumors: Analysis of 136 Cases
ABSTRACT Objective Distant metastases in the head and neck region are rare, often posing challenges for ENT specialists and being of crucial importance in the management of infraclavicular primary tumors. Methods The case series presented here aims to outline the relevant aetiologies and clinical presentation in the head and neck region.
Achim M. Franzen +3 more
wiley +1 more source
Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh +3 more
wiley +1 more source
Prostate Cancer Development, Progression, and Therapy
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin +9 more
wiley +1 more source
Current diagnostic tests for lower urinary tract symptoms lack the ability to assess tissue‐level alterations in the bladder wall. This study introduces an approach for simultaneous high‐resolution 3D T1, T2, and proton density mapping of the bladder wall using magnetic resonance fingerprinting combined with a self‐supervised deep learning ...
Shane A. Wells +5 more
wiley +1 more source
Aparelho urogenital: parte 2 [Embriologia]
Apresenta estudo embriológico do sistema urogenital através de modelos esquemáticos do sistema genital indiferenciado (masculino e feminino)Componente Curricular::Educação Superior::Ciências da Saúde ...
Santos, Thamara B. B. dos +1 more
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