Results 1 to 10 of about 835 (215)

Maleate salts of bedaquiline [PDF]

Acta Crystallographica Section E Crystallographic Communications, 2021
Bedaquiline is one of two important new drugs for the treatment of drug-resistant tuberculosis (TB). It is marketed in the US as its fumarate salt, but only a few salts of bedaquiline have been structurally described so far. We present here five crystal structures of bedaquilinium maleate {systematic name: [4-(6-bromo-2-methoxyquinolin-3-yl)-3-hydroxy ...
Matthias Zeller, Susan Bogdanowich-Knipp, Pamela Smith, Dale K. Purcell, Mercy Okezue, Daniel T. Smith, Stephen R. Byrn, Kari L. Clase   +7 more
openaire   +3 more sources

Unusual Formation of 1,2,4-Oxadiazine Core in Reaction of Amidoximes with Maleic or Fumaric Esters

Molecules, 2022
We have developed a simple and convenient method for the synthesis of 3-aryl- and 3-hetaryl-1,2,4-oxadiazin-5-ones bearing an easily functionalizable (methoxycarbonyl)methyl group at position 6 via the reaction of aryl or hetaryl amidoximes with maleates
Sofia I. Presnukhina, Marina V. Tarasenko, Kirill K. Geyl, Svetlana O. Baykova, Sergey V. Baykov, Anton A. Shetnev, Vadim P. Boyarskiy   +6 more
doaj   +1 more source

Rheokinetic study of crosslinking of α,ω-dihydroxy oligo(alkylene maleate)s with a trisisocyanate [PDF]

Journal of the Serbian Chemical Society, 2003
The crosslinking reaction of three series of α,ω-dihydroxy oligo(alkylene maleate)s with a trifunctional isocyanate was followed by dynamic mechanical analysis and FTIR spectroscopy.
Dunjić Branko, Đonlagić Jasna A., Vukašinović Slavko, Sepulchre Maurice, Sepulchre Marie-Odile, Spassky Nicolas   +5 more
doaj   +1 more source

Delineating Pixantrone Maleate's adroit activity against cervical cancer proteins through multitargeted docking-based MM\GBSA, QM-DFT and MD simulation.

PLoS ONE, 2023
Cervical cancer poses a substantial worldwide health challenge, especially in low- and middle-income nations, caused by high-risk types of human papillomavirus.
Hassan Hussain Almasoudi, Mohammed H Nahari, Abdulfattah Yahya M Alhazmi, Saleh Hussain A Almasabi, Fares Saeed H Al-Mansour, Mohammed Ageeli Hakami   +5 more
doaj   +1 more source

Trimipraminium maleate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
THE TITLE COMPOUND [SYSTEMATIC NAME: 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethyl-propan-1-aminium hydrogen maleate], C(20)H(27)N(2) (+)·C(4)H(3)O(4) (-), a maleate salt of trimipramine, crystallizes with four independent cation-anion pairs in the asymmetric unit.
Jasinski, Jerry P., Butcher, Ray J., Hakim Al-Arique, Q. N. M., Yathirajan, H. S., Narayana, B.   +4 more
openaire   +4 more sources

Oxygenated Diesel Fuels and Their Effect on PM Emissions

Applied Sciences, 2022
Particulate matter (PM) emitted by diesel engines is one of the most harmful components of exhaust gases, including its carcinogenic effect. Due to the widespread use of diesel engines, the health effects of PM emissions affect millions of people around ...
Miłosław Kozak, Jerzy Merkisz
doaj   +1 more source

Identification of putative steroid receptor antagonists in bottled water: combining bioassays and high-resolution mass spectrometry. [PDF]

PLoS ONE, 2013
Endocrine disrupting chemicals (EDCs) are man-made compounds interfering with hormone signaling and thereby adversely affecting human health. Recent reports provide evidence for the presence of EDCs in commercially available bottled water, including ...
Martin Wagner, Michael P Schlüsener, Thomas A Ternes, Jörg Oehlmann   +3 more
doaj   +1 more source

Flunarizinium hydrogen maleate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2013
In the cation of the title salt {systematic name: 4-[bis-(4-fluoro-phen-yl)meth-yl]-1-[(2E)-3-phenyl-prop-2-en-1-yl]piperazin-1-ium hydrogen maleate}, C26H27F2N2 (+)·C4H3O4 (-), the protonated piperazine ring is in a chair conformation. The dihedral angle between the 4-fluoro-phenyl rings is 68.2 (2)°.
Kavitha, C. N., Jasinski, J. P., Matar, S. M., Yathirajan, H. S., Ramesha, A. R.   +4 more
openaire   +4 more sources

Creatininium hydrogen maleate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
In the title compound, C(4)H(8)N(3)O(+)·C(4)H(3)O(4) (-), the cations and anions are linked through N-H⋯O hydrogen bonds making a ionic pair with an R(2) (2)(8) ring motif. These ionic pairs are further connected through another N-H⋯O hydrogen bond, leading to an R(6) (6)(16) ring motif around the inversion centres of the unit cell. These approximately
A. Jahubar Ali, S. Athimoolam, S. Asath Bahadur   +2 more
openaire   +3 more sources

Interaction between maleic acid and N-R-furfurylamines: crystal structure of 2-methyl-N-[(5-phenylfuran-2-yl)methyl]propan-2-aminium (2Z)-3-carboxyacrylate and N-[(5-iodofuran-2-yl)methyl]-2-methylpropan-2-aminium (2Z)-3-carboxyprop-2-enoate

Acta Crystallographica Section E: Crystallographic Communications, 2017
The title molecular salts, C15H20NO+·C4H3O4−, (I), and C9H15INO+·C4H3O4−, (II), have very similar molecular geometries for both cation and anion. The anions of both (I) and (II) are practically planar (r.m.s. deviations = 0.062 and 0.072 Å, respectively)
Elisaveta A. Kvyatkovskaya, Vladimir P. Zaytsev, Fedor I. Zubkov, Pavel V. Dorovatovskii, Yan V. Zubavichus, Victor N. Khrustalev   +5 more
doaj   +1 more source