Results 1 to 10 of about 3,546,819 (341)

Arsenic trioxide induces cell cycle arrest and affects Trk receptor expression in human neuroblastoma SK-N-SH cells

Biological Research, 2018
Background Arsenic trioxide (As2O3), a drug that has been used in China for approximately two thousand years, induces cell death in a variety of cancer cell types, including neuroblastoma (NB).
Xilin Xiong, Yang Li, Ling Liu, Kai Qi, Chi Zhang, Yueqin Chen, Jianpei Fang   +6 more
doaj   +1 more source

LncRNA DILA1 inhibits Cyclin D1 degradation and contributes to tamoxifen resistance in breast cancer

Nature Communications, 2020
Cyclin D1 is involved in tamoxifen resistance in breast cancer (BC) but how it is regulated is unclear. Here, the authors demonstrate that the LncRNA DILA1 contributes to tamoxifen resistance in breast cancer by binding to Cyclin D1 and preventing its ...
Qianfeng Shi, Yudong Li, Shunying Li, Liang Jin, Hongna Lai, Yanqing Wu, Zijie Cai, Mengdi Zhu, Qian Li, Ying Li, Jingru Wang, Yujie Liu, Zongqi Wu, Erwei Song, Qiang Liu   +14 more
doaj   +1 more source

Bmi-1-induced miR-27a and miR-155 promote tumor metastasis and chemoresistance by targeting RKIP in gastric cancer

Molecular Cancer, 2020
Background We previously reported an inverse relationship between B cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) and Raf kinase inhibitory protein (RKIP), which is associated with the prognosis of gastric cancer (GC).
Yaqing Li, Zhenfeng Tian, Ying Tan, Guoda Lian, Shangxiang Chen, Shaojie Chen, Jiajia Li, Xuanna Li, Kaihong Huang, Yinting Chen   +9 more
doaj   +1 more source

New and emerging therapeutic options for malignant pleural mesothelioma: review of early clinical trials. [PDF]

, 2015
Malignant pleural mesothelioma (MPM) is a rare tumor that is challenging to control. Despite some benefit from using the multimodality-approach (surgery, combination chemotherapy and radiation), survival remains poor. However, current research produced a
Cameron, Robert B, Kotova, Svetlana, Wong, Raymond M   +2 more
core   +2 more sources

Long noncoding RNA H19 upregulates vascular endothelial growth factor A to enhance mesenchymal stem cells survival and angiogenic capacity by inhibiting miR-199a-5p

Stem Cell Research & Therapy, 2018
Background Currently, the overall therapeutic efficiency of mesenchymal stem cells (MSCs) transplantation for the treatment of cardiovascular disease is not satisfactory.
Jingying Hou, Lingyun Wang, Quanhua Wu, Guanghui Zheng, Huibao Long, Hao Wu, Changqing Zhou, Tianzhu Guo, Tingting Zhong, Lei Wang, Xuxiang Chen, Tong Wang   +11 more
doaj   +1 more source

Target-specific glioma therapy in an immunocompetent mouse model : meeting abstract [PDF]

, 2006
Objective: Establishment of an immunocompetent mouse model representing the typical progressive stages observed in malignant human gliomas for the in vivo evaluation of novel target-specific regimens.
Baus, Daniela, Kreuter, Jörg, Kögel, Donat, Masri, J., Pfitzner, Edith, Raabe, Andreas, Seifert, Volker, Weissenberger, Jakob   +7 more
core  

P755: HYPERFERRITINEMIA IS A PREDICTIVE BIOMARKER OF POOR CLINICAL OUTCOMES IN CMML

HemaSphere, 2022
L. E. Aguirre, S. Ball, A. Jain, N. Al Ali, D. Sallman, A. Kuykendall, K. Sweet, J. Lancet, E. Padron, R. Komrokji   +9 more
doaj   +1 more source

TYK2 promotes malignant peripheral nerve sheath tumor progression through inhibition of cell death [PDF]

, 2019
BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas that arise most commonly in the setting of the Neurofibromatosis Type 1 (NF1) cancer predisposition syndrome.
Bu, Xianzhang, Godec, Abigail, Hirbe, Angela C, Qin, Wenjing, Shao, Jieya, Tao, Yu, Zhang, Xiaochun, Zhu, Cuige   +7 more
core   +2 more sources

Does establishing a preoperative nomogram including ultrasonographic findings help predict the likelihood of malignancy in patients with microcalcifications?

Cancer Imaging, 2019
Background Mammography (MG) is highly sensitive for detecting microcalcifications, but has low specificity. This study investigates whether establishing a preoperative nomogram including ultrasonographic findings can help predict the likelihood of ...
Hongli Wang, Jianguo Lai, Jiao Li, Ran Gu, Fengtao Liu, Yue Hu, Jingsi Mei, Xiaofang Jiang, Shiyu Shen, Fengyan Yu, Fengxi Su   +10 more
doaj   +1 more source

Commentary [Decompressive craniectomy in patients with cerebral infarction due to malignant vasospasm after aneurysmal subarachnoid hemorrhage] [PDF]

, 2012
Commentary: article "Decompressive craniectomy in patients with cerebral infarction due to malignant vasospasm after aneurysmal subarachnoid hemorrhage" on page 251 http://www.ncbi.nlm.nih.gov/pmc/articles ...
Archavlis, Eleftherios
core