Results 121 to 130 of about 3,636,929 (290)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Total discrimination of peritoneal malignant ascites from cirrhosis- and hepatocarcinoma-associated ascites by assays of ascitic cholesterol and lactate dehydrogenase [PDF]

, 1994
Giuseppe Castaldo, G Oriani, L. Cimino, Matilde Topa, I Mostarda, Luigi Castellano, C. Del Vecchio‐Blanco, G Budillon, Francesco Salvatore, Lucia Sacchetti   +9 more
openalex   +1 more source

Development of adaptive stereotactic radiotherapy method in treatment of primary malignant glial tumors in the brain [PDF]

, 2022
S. G. Vlasov, M.A. Yengibaryan, A.I. Shikhlyarova, P.G. Sakun, V.I. Voshedsky, O.G. Rodionova, E.A. Karnaukhova, A.A. Solntseva, V.E. Khatyushin, O.V. Pandova, Nataliya S. Kuznetsova, S.N. Kabanov, M.A. Teplyakova   +12 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Differential diagnosis of breast mucinous carcinoma with an oval shape from fibroadenoma based on ultrasonographic features

BMC Women's Health
Background Approximately 50% of breast mucinous carcinomas (MCs) are oval and have the possibility of being misdiagnosed as fibroadenomas (FAs). We aimed to identify the key features that can help differentiate breast MC with an oval shape from FA on ...
Hongli Wang, Yue Hu, Cui Tan, Ran Gu, Yudong Li, Liang Jin, Xiaofang Jiang, Jingsi Mei, Qiang Liu, Chang Gong   +9 more
doaj   +1 more source

Target-specific glioma therapy in an immunocompetent mouse model : meeting abstract [PDF]

, 2006
Objective: Establishment of an immunocompetent mouse model representing the typical progressive stages observed in malignant human gliomas for the in vivo evaluation of novel target-specific regimens.
Baus, Daniela, Kreuter, Jörg, Kögel, Donat, Masri, J., Pfitzner, Edith, Raabe, Andreas, Seifert, Volker, Weissenberger, Jakob   +7 more
core  

Malignant hypertension: a syndrome associated with low plasma kininogen and kinin potentiating factor. [PDF]

, 1981
Fernando Antônio de Almeida, R C Stella, A Voos, H Ajzen, Arthur Barcelos Ribeiro   +4 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Induction of p27 contributes to inhibitory effect of isorhapontigenin (ISO) on malignant transformation of human urothelial cells

, 2022
Maowen Huang, Xiaohui Hua, Jiheng Xu, Zhongxian Tian, Jiajing Wang, Heng-Chao Chen, Xuyao Wang, Peng Shu, Hongyan Ye, Jianfeng Shu, Chuanshu Huang   +10 more
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source