Results 301 to 310 of about 2,812,752 (406)

Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases

Advanced Materials, EarlyView.
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu, Rockie Haiyao Ding, Zixuan Zhao, Clara Yieh Lin Chong, Ruochii You, Hengjia Zhou, Dong Hua Seah, Wei Qiang Leow, Hong Kit Lim, Sukanya Shyamasundar, Kanishka Fernando, Fathima Farzana Kuthubudeen, Gillian Ng, Chor Yong Tay, Narayanan Gopalakrishna Iyer, Chin‐Ann Johnny Ong, Eliza Li Shan Fong   +16 more
wiley   +1 more source

TREATMENT OF THE MALIGNANT CHOLERA AT THE CHOLERA HOSPITAL, WESTMINSTER. [PDF]

Jonelle E. Wright
openalex   +1 more source

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

Advanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang, Hengji Zhan, Bolin Pan, Leli Zeng, Zehua Chen, Sen Liu, Qiang Zhang, Xuwei Hong, Junlin Lu, Xinrou Lin, Xiao Zhao, Jiajian Lai, Kaiwen Jie, Ye Li, Jianmei Zhong, Shengmeng Peng, Siting Chen, Changhao Chen, Wenlong Zhong, Shaoxu Wu, Yihang Pan, Tianxin Lin, Xu Chen   +22 more
wiley   +1 more source

A role for early surgical intervention in childhood low-grade glioma? Illustrative case. [PDF]

J Neurosurg Case Lessons
Jung Y, Dirks J, Hawkins C, Tabori U, Das A, Bennett J, Dirks P, Quon JL.   +7 more
europepmc   +1 more source

On a Hormone-Dependent Spontaneous, Malignant Ascites Tumour in Rats

, 1959
Stig Kullander
openalex   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Differentiation of benign and malignant breast lesions by ultrasound localization microscopy. [PDF]

Insights Imaging
Li J, Wei C, Ying T, Liu Y, Wang R, Li M, Feng C, Sun D, Zheng Y.   +8 more
europepmc   +1 more source

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

Advanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong, M Sriram, Hepi Hari Susapto, Yixuan Li, Yuan Jiang, Nicolas H. Voelcker, Jennifer L. Young, Andrew W. Holle, Roey Elnathan   +8 more
wiley   +1 more source

Optimized YOLOv8 for enhanced breast tumor segmentation in ultrasound imaging. [PDF]

Discov Oncol
Mostafa AM, Alaerjan AS, Aldughayfiq B, Allahem H, Mahmoud AA, Said W, Shabana H, Ezz M.   +7 more
europepmc   +1 more source

Ionic Liquid‐Reinforced Multifunctional Hydrogel for the Treatment of Enterocutaneous Fistula

Advanced Materials, EarlyView.
ECFGel is a multifunctional hydrogel engineered to treat infection‐associated ECFs. ECFGel demonstrates outstanding mechanical and biological properties, facilitating easy application, reliable occlusion, and sterilization, while promoting effective healing of infected fistula tracts.
Jinjoo Kim, Hyeongseop Keum, Hassan Albadawi, Ismail Altinbasak, Furkan Yavuz, Erin H. Graf, Nitin Mishra, Rahmi Oklu   +7 more
wiley   +1 more source