Results 31 to 40 of about 13,665 (250)

Langerhans cell histiocytosis: current advances in molecular pathogenesis

open access: yesFrontiers in Immunology, 2023
Langerhans cell histiocytosis (LCH) is a rare and clinically heterogeneous hematological disease characterized by the accumulation of mononuclear phagocytes in various tissues and organs.
Tommaso Sconocchia   +4 more
doaj   +1 more source

Clinical pathological characteristics of pelvic bone tumors [PDF]

open access: yesMedicinski Podmladak, 2021
Introduction: Bone tumors are rare neoplasms whose therapy depends on the location. Pelvic bones represent a special anatomical entity diagnosis and therapy of pelvic tumors in addition to the pathohistological type largely depends on the anatomical ...
Starčević Darko   +4 more
doaj   +1 more source

Localized Langerhans cell histiocytosis masquerading as Brodie s abscess in a 2-year-old child: a case report [PDF]

open access: yes, 2016
Langerhans cell histiocytosis (LCH), formerly known as histiocytosis X, refers to a spectrum of diseases characterized by idiopathic proliferation of histiocytes that produce either focal (localized LCH) or systemic manifestations (Hand–Schüller ...
Chang, Wei-Fang   +4 more
core   +1 more source

Somatic mutations in solid tumors: a spectrum at the service of diagnostic armamentarium or an indecipherable puzzle? The morphological eyes looking for BRAF and somatic molecular detections on cyto-histological samples [PDF]

open access: yes, 2016
This review article deals with the analysis and the detection of the morphological features associated with somatic mutations, mostly BRAF(V600E) mutation, on both cytological and histological samples of carcinomas.
Abildgaard   +112 more
core   +1 more source

Langerhans cell histiocytosis [PDF]

open access: yes, 1998
The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations.
Atallah, Álvaro Nagib   +10 more
core   +2 more sources

Oral manifestation of Langerhans cell histiocytosis: a case report

open access: yesBMC Oral Health, 2018
Background Bone necrosis of the jaw is a serious condition with a broad differential diagnosis of pathologies such as cutaneous histiocytosis, bone metastases or malignant tumours. In addition to the most common cause, medication related osteonecrosis of
Julia Luz   +5 more
doaj   +1 more source

Common Acute Lymphoblastic Leukemia Ph+ Following Langerhans Cell Histiocytosis in a Multi-Malformed Child with INV (9) (p12;q13) (mat):Case Report [PDF]

open access: yes, 2010
The occurrence of Langerhans cell histiocytosis (LCH) and another malignancy in the same patient is infrequent but has been recognized. The genetic changes that could be responsible for LCH and/or concomitant leukemia development are obscure. To the best
Pavelić, Jasminka   +2 more
core   +1 more source

Langerhans Cell Histiocytosis of the Thyroid with Multiple Cervical Lymph Node Involvement Accompanying Metastatic Thyroid Papillary Carcinoma

open access: yesCase Reports in Pathology, 2014
A 37-year-old male case was admitted with goiter. Ultrasonography of thyroid showed a 5 cm cystic nodule in the left lobe with a 1.5 cm solid component. Fine needle aspiration biopsy revealed atypia of undetermined significance or follicular lesion.
A. Bahar Ceyran   +5 more
doaj   +1 more source

Diagnostic Challenge in Rapidly Growing Langerhans Cell Histiocytosis with Aneurysmal Bone Cyst in the Maxilla: A Case Report

open access: yesDiagnostics, 2022
Langerhans cell histiocytosis (LCH) is a rare neoplastic disorder characterized by the clonal proliferation of CD1a +/CD 207 + dendritic cells, whose features are similar to those of epidermal Langerhans cells.
Ye Rin Hwang   +3 more
doaj   +1 more source

Multisystem Langerhans cell histiocytosis coexisting with metastasizing adenocarcinoma of the lung: A case report [PDF]

open access: yes, 2013
Introduction. Langerhans cell histiocytosis (LCH) is an uncommon disease of unknown etiology characterized by uncontrolled proliferation and infiltration of various organs by Langerhans cells. Case report. We presented a 54-year-old man, heavy smoker,
Eri Živka   +6 more
core   +1 more source

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