Langerhans cell histiocytosis: current advances in molecular pathogenesis
Langerhans cell histiocytosis (LCH) is a rare and clinically heterogeneous hematological disease characterized by the accumulation of mononuclear phagocytes in various tissues and organs.
Tommaso Sconocchia +4 more
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Clinical pathological characteristics of pelvic bone tumors [PDF]
Introduction: Bone tumors are rare neoplasms whose therapy depends on the location. Pelvic bones represent a special anatomical entity diagnosis and therapy of pelvic tumors in addition to the pathohistological type largely depends on the anatomical ...
Starčević Darko +4 more
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Localized Langerhans cell histiocytosis masquerading as Brodie s abscess in a 2-year-old child: a case report [PDF]
Langerhans cell histiocytosis (LCH), formerly known as histiocytosis X, refers to a spectrum of diseases characterized by idiopathic proliferation of histiocytes that produce either focal (localized LCH) or systemic manifestations (Hand–Schüller ...
Chang, Wei-Fang +4 more
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Somatic mutations in solid tumors: a spectrum at the service of diagnostic armamentarium or an indecipherable puzzle? The morphological eyes looking for BRAF and somatic molecular detections on cyto-histological samples [PDF]
This review article deals with the analysis and the detection of the morphological features associated with somatic mutations, mostly BRAF(V600E) mutation, on both cytological and histological samples of carcinomas.
Abildgaard +112 more
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Langerhans cell histiocytosis [PDF]
The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations.
Atallah, Álvaro Nagib +10 more
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Oral manifestation of Langerhans cell histiocytosis: a case report
Background Bone necrosis of the jaw is a serious condition with a broad differential diagnosis of pathologies such as cutaneous histiocytosis, bone metastases or malignant tumours. In addition to the most common cause, medication related osteonecrosis of
Julia Luz +5 more
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Common Acute Lymphoblastic Leukemia Ph+ Following Langerhans Cell Histiocytosis in a Multi-Malformed Child with INV (9) (p12;q13) (mat):Case Report [PDF]
The occurrence of Langerhans cell histiocytosis (LCH) and another malignancy in the same patient is infrequent but has been recognized. The genetic changes that could be responsible for LCH and/or concomitant leukemia development are obscure. To the best
Pavelić, Jasminka +2 more
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A 37-year-old male case was admitted with goiter. Ultrasonography of thyroid showed a 5 cm cystic nodule in the left lobe with a 1.5 cm solid component. Fine needle aspiration biopsy revealed atypia of undetermined significance or follicular lesion.
A. Bahar Ceyran +5 more
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Langerhans cell histiocytosis (LCH) is a rare neoplastic disorder characterized by the clonal proliferation of CD1a +/CD 207 + dendritic cells, whose features are similar to those of epidermal Langerhans cells.
Ye Rin Hwang +3 more
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Multisystem Langerhans cell histiocytosis coexisting with metastasizing adenocarcinoma of the lung: A case report [PDF]
Introduction. Langerhans cell histiocytosis (LCH) is an uncommon disease of unknown etiology characterized by uncontrolled proliferation and infiltration of various organs by Langerhans cells. Case report. We presented a 54-year-old man, heavy smoker,
Eri Živka +6 more
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