Results 81 to 90 of about 72,644 (316)

Nucleolin and nucleophosmin expression patterns in pulmonary adenocarcinoma invading the pleura and in pleural malignant mesothelioma

open access: yesThoracic Cancer, 2020
Background Visceral pleural invasion (VPI) in adenocarcinoma of the lung is considered a poor prognostic factor. The purpose of this study was to analyze nucleolin and nucleophosmin expression in pulmonary adenocarcinoma (PA) with VPI and in pleural ...
Marek Masiuk   +4 more
doaj   +1 more source

Diagnostic Challenges in Epithelioid Pleural Mesothelioma: Case Series with Support from Electron Microscopy

open access: yesDiagnostics, 2021
The histological diagnosis of pleural epithelioid mesothelioma can be difficult in the case of rare variants or in the definition of neoplasm origin in patients with previous or concomitant tumours.
Francesco Fortarezza   +8 more
doaj   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Surgery in Malignant Pleural Mesothelioma

open access: yesJournal of Thoracic Oncology, 2018
Surgical intervention plays an important role in the diagnosis, staging, and treatment of malignant pleural mesothelioma (MPM) and can be applied with curative or palliative intent. The overall aim of surgery should be, as in any oncologic surgery, the macroscopic complete resection (MCR) of the tumor.
Iaslc Mesothelioma Taskforce   +2 more
openaire   +4 more sources

Switching off malignant mesothelioma : exploiting the hypoxic microenvironment [PDF]

open access: yes, 2017
Malignant mesotheliomas are aggressive, asbestos-related cancers with poor patient prognosis, typically arising in the mesothelial surfaces of tissues in pleural and peritoneal cavity.
Bennewith, KL   +5 more
core   +1 more source

Multimodal treatment for resectable epithelial type malignant pleural mesothelioma

open access: yesWorld Journal of Surgical Oncology, 2004
Background Malignant pleural mesothelioma is a rare malignancy. The outcome remains poor despite complete surgical resection. Patients and methods Eleven patients with histologicaly proven epithelial type malignant pleural mesothelioma undergoing ...
Fukuyama Yasuro   +6 more
doaj   +1 more source

Simultaneous tongue metastasis from malignant pleural mesothelioma: Case report and literature review

open access: yesThoracic Cancer, 2021
Malignant pleural mesothelioma (MPM) is a rare neoplasm of the serosal membranes. MPM usually manifests as local invasion, rarely with distant haematogenous metastases in different organs. Few cases of tongue metastasis have been documented.
Chuan Huang, Xue Yang
doaj   +1 more source

KEYNOTE‐A17: First‐Line Pembrolizumab Plus Cisplatin–Pemetrexed in Japanese Participants With Advanced Pleural Mesothelioma

open access: yesCancer Science, EarlyView.
In the phase 1b KEYNOTE‐A17 study of first‐line pembrolizumab plus chemotherapy in Japanese participants with advanced pleural mesothelioma (PM), 2 of 18 participants (11%) evaluated experienced dose‐limiting toxicities. The objective response rate among all 19 participants in the study was 74%, with 14 participants achieving a partial response and a ...
Takashi Kijima   +11 more
wiley   +1 more source

Heterogeneity in Immune Cell Content in Malignant Pleural Mesothelioma

open access: yesInternational Journal of Molecular Sciences, 2018
Malignant pleural mesothelioma (MPM) is a highly aggressive cancer with limited therapy options and dismal prognosis. In recent years, the role of immune cells within the tumor microenvironment (TME) has become a major area of interest.
J. Minnema-Luiting   +3 more
semanticscholar   +1 more source

Malignant pleural mesothelioma in Italy

open access: yesIndian Journal of Occupational and Environmental Medicine, 2009
This study reviews a series of 811 malignant pleural mesothelioma cases, diagnosed at hospitals in Trieste and Monfalcone districts of north eastern Italy, a narrow coastal strip with a population of about three lakh, in the period 1968-2008. The diagnosis was based on histological examination in 801 cases, and cytological findings in 10.
Bianchi, Claudio, Bianchi, Tommaso
openaire   +4 more sources

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