Results 81 to 90 of about 72,644 (316)
Background Visceral pleural invasion (VPI) in adenocarcinoma of the lung is considered a poor prognostic factor. The purpose of this study was to analyze nucleolin and nucleophosmin expression in pulmonary adenocarcinoma (PA) with VPI and in pleural ...
Marek Masiuk+4 more
doaj +1 more source
The histological diagnosis of pleural epithelioid mesothelioma can be difficult in the case of rare variants or in the definition of neoplasm origin in patients with previous or concomitant tumours.
Francesco Fortarezza+8 more
doaj +1 more source
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley +1 more source
Surgery in Malignant Pleural Mesothelioma
Surgical intervention plays an important role in the diagnosis, staging, and treatment of malignant pleural mesothelioma (MPM) and can be applied with curative or palliative intent. The overall aim of surgery should be, as in any oncologic surgery, the macroscopic complete resection (MCR) of the tumor.
Iaslc Mesothelioma Taskforce+2 more
openaire +4 more sources
Switching off malignant mesothelioma : exploiting the hypoxic microenvironment [PDF]
Malignant mesotheliomas are aggressive, asbestos-related cancers with poor patient prognosis, typically arising in the mesothelial surfaces of tissues in pleural and peritoneal cavity.
Bennewith, KL+5 more
core +1 more source
Multimodal treatment for resectable epithelial type malignant pleural mesothelioma
Background Malignant pleural mesothelioma is a rare malignancy. The outcome remains poor despite complete surgical resection. Patients and methods Eleven patients with histologicaly proven epithelial type malignant pleural mesothelioma undergoing ...
Fukuyama Yasuro+6 more
doaj +1 more source
Malignant pleural mesothelioma (MPM) is a rare neoplasm of the serosal membranes. MPM usually manifests as local invasion, rarely with distant haematogenous metastases in different organs. Few cases of tongue metastasis have been documented.
Chuan Huang, Xue Yang
doaj +1 more source
In the phase 1b KEYNOTE‐A17 study of first‐line pembrolizumab plus chemotherapy in Japanese participants with advanced pleural mesothelioma (PM), 2 of 18 participants (11%) evaluated experienced dose‐limiting toxicities. The objective response rate among all 19 participants in the study was 74%, with 14 participants achieving a partial response and a ...
Takashi Kijima+11 more
wiley +1 more source
Heterogeneity in Immune Cell Content in Malignant Pleural Mesothelioma
Malignant pleural mesothelioma (MPM) is a highly aggressive cancer with limited therapy options and dismal prognosis. In recent years, the role of immune cells within the tumor microenvironment (TME) has become a major area of interest.
J. Minnema-Luiting+3 more
semanticscholar +1 more source
Malignant pleural mesothelioma in Italy
This study reviews a series of 811 malignant pleural mesothelioma cases, diagnosed at hospitals in Trieste and Monfalcone districts of north eastern Italy, a narrow coastal strip with a population of about three lakh, in the period 1968-2008. The diagnosis was based on histological examination in 801 cases, and cytological findings in 10.
Bianchi, Claudio, Bianchi, Tommaso
openaire +4 more sources