Results 251 to 260 of about 389,072 (294)

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

open access: yesAdvanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li   +17 more
wiley   +1 more source

Implications of Podoplanin Overexpression in the Malignant Transformation of Oral Potentially Malignant Disorders: A Systematic Review and Meta-Analysis. [PDF]

open access: yesCancers (Basel)
Correa-Fernández M   +4 more
europepmc   +1 more source

Is Aneuploidy a Consistent Marker for Malignant Transformation Risk in Oral Lichen Planus? [PDF]

open access: yesHead Neck Pathol
Pessing-Shabi A   +5 more
europepmc   +1 more source

Malignant Transformation of Renal Cyst with Bosniak I Features. [PDF]

open access: yesDiagnostics (Basel)
Ćulap S   +7 more
europepmc   +1 more source

Malignant Transformation in Craniopharyngioma

Neurosurgery, 1988
Abstract Malignant transformation in a craniopharyngioma has not been described previously. A 49-year-old woman presented with recurrence of a suprasellar craniopharyngioma diagnosed 35 years previously. The patient had been treated surgically for recurrence on five occasions.
G A, Nelson   +3 more
openaire   +2 more sources

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