Results 221 to 230 of about 1,736,515 (318)

Obese patients with malignant tumor: a case series and literature review. [PDF]

Discov Oncol
Liang P, Zhu MY, Yang R, Wang X, Yue H, Zheng Y, Liu J, Lv YL, Shan B.   +8 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Clinical features and risk factors for poor prognosis in malignant tumor patients with pulmonary embolism: a case control study. [PDF]

Thromb J
Dong K, Kong H, Wang L, Yu Z, Lu X, Cui Z, Yang J, Xia Y, Zhang B, Li Z.   +9 more
europepmc   +1 more source

MALIGNANT TUMORS OF THE TESTICLE

Annals of Surgery, 1928
openaire   +3 more sources

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Evidence summary for the management of sleep disorders after malignant tumor surgery. [PDF]

Front Neurol
Yang C, Liu Y, Xiao B, Yang J, Zeng Q, Tan R, Ma H.   +6 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Roles and Prospective Applications of Ferroptosis Suppressor Protein 1 (FSP1) in Malignant Tumor Treatment. [PDF]

Curr Oncol
Jin Z, Zhang Q, Pan Y, Chen H, Zhou K, Cai H, Huang P.   +6 more
europepmc   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Advancing surgical techniques: a first application of remote robotic pancreaticoduodenectomy for resectable malignant tumor. [PDF]

Hepatobiliary Surg Nutr
Zou WB, Wu ZP, Chen WL, Fang NB, Yang J, Zhao GD.   +5 more
europepmc   +1 more source