Results 31 to 40 of about 210,720 (264)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Clinical and microbiological characteristics of healthcare-associated infections in a tertiary care pediatric hospital

open access: yesEgyptian Pediatric Association Gazette, 2017
Background and aim: Healthcare-associated infections (HAIs) are an important cause of prolonged hospital stay. This study was conducted to assess the incidence, causative organisms and risk factors of HAIs in pediatric patients. Subjects and methods: Our
Rasha H. Hassan   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Pelvic Floor Dysfunction in People with Eating Disorders and the Acute Effect of Different Interventions – A Retrospective Cohort Study

open access: yesClinical and Experimental Obstetrics & Gynecology
Background: Studies suggest that there is an association between eating disorders and pelvic floor dysfunction (PFD), although the contribution of PFD toward symptomatology and interventions to improve these symptoms in the eating disorder population is ...
Monica Williams   +4 more
doaj   +1 more source

Prevalence of Malnutrition in Patients with Head and Neck Cancer in Yazd, Iran [PDF]

open access: yesInternational Journal of Nutrition Sciences, 2019
Background: Head and neck cancers are accounted for 4.9% of all cancers worldwide. The aim of this study was to evaluate the prevalence of malnutrition in patients with head and neck cancers in Yazd, Iran.Methods: Eighty-nine patients with locally ...
Mohammad Hossein Dadgarnia   +4 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Zinc levels in severe eating disorders

open access: yesJournal of Eating Disorders
Purpose Severe eating and feeding disorders including Anorexia Nervosa of both restricting (AN-R) and binge-purge (AN-BP) subtypes and Avoidant Restrictive Food Intake Disorder (ARFID) lead to multiple macronutrient and micronutrient deficiencies ...
Kara Leach   +5 more
doaj   +1 more source

Assessment of malnutrition in patients with liver cirrhosis using protein calorie malnutrition (PCM) score verses bio-electrical impedance analysis (BIA)

open access: yesBMC Research Notes, 2018
Objective Malnutrition is a common problem in patients with liver cirrhosis and tools for nutritional assessment are under debate. We conducted this study to assess prevalence of malnutrition in cirrhotic patients using PCM score and BIA. Additionally we
Om Parkash   +3 more
doaj   +1 more source

Clinico-biochemical profile of sick children with severe acute malnutrition

open access: yesJournal of Family Medicine and Primary Care, 2020
Objective: Severe acute malnutrition (SAM) classified as edematous and marasmus, however, Kwashiorker represents the most severe phenotype of edematous malnutrition.
Dhilip Kumar   +2 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

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