Results 1 to 10 of about 16,726 (54)
Innovative Biosystems and Bioengineering, 2022 Проблематика. Кількість біогенних магнітних наночастинок (БМН), наявних в органах і тканинах людини у формі магнетиту (феримагнітного оксиду заліза), збільшується при онкологічних і нейродегенеративних захворюваннях.
Anna Spiridonova, Svitlana Gorobets
doaj +1 more source
International Journal on Biological Sciences, 2023 Diabetic kidney disease (DKD) is a global health issue that presents a complex pathogenesis and limited treatment options. To provide guidance for precise therapies, it is crucial to accurately identify the pathogenesis of DKD.
Yong Liu +9 more
semanticscholar +1 more source
Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity
International Journal of Molecular Sciences, 2023 Cholesterol is a key component of all mammalian cell membranes. Disruptions in cholesterol metabolism have been observed in the context of various diseases, including neurodegenerative disorders such as Alzheimer’s disease (AD).
Taylor C Harned +6 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance The mitochondria-associated endoplasmic reticulum membrane (MAM) is a highly dynamic structure that serves as a signaling platform for a variety of cellular activities, including Ca2+ homeostasis.
Truong Thi My Nhung +19 more
semanticscholar +1 more source
Critical reviews in analytical chemistry, 2023 The rapid growth of biotherapeutic industry, with more and more complex molecules entering the market, forces the need for advanced analytical platforms that can quickly and accurately identify and quantify product quality attributes.
Silvia Millán-Martín +6 more
semanticscholar +1 more source
Ratiometric measurement of MAM Ca2+ dynamics using a modified CalfluxVTN
Nature Communications, 2023 Mitochondria-associated ER membrane (MAM) is a structure where these calcium-regulating organelles form close physical contact sites for efficient Ca2+ crosstalk.
Eunbyul Cho +10 more
semanticscholar +1 more source
Clinical science, 2023 Mitochondria-associated endoplasmic reticulum membranes (MAMs) regulate ATG14- and Beclin1-mediated mitophagy and play key roles in the development of diabetic nephropathy (DN).
Lin Sun +13 more
semanticscholar +1 more source
Multi-attribute method (MAM) to assess analytical comparability of adalimumab biosimilars.
Journal of Pharmaceutical and Biomedical Analysis, 2023 Adalimumab drug product (Humira ®), the first fully human monoclonal antibody (mAb) approved by FDA in 2002, led the top ten list of best-selling mAbs in 2018 and has been the most profitable drug in the world. With the expiration of patent protection in
Silvia Millán-Martín +3 more
semanticscholar +1 more source
Journal of Clinical Medicine, 2023 Background: The roles of mitochondria and the endoplasmic reticulum (ER) in the progression of hepatocellular carcinoma (HCC) are well established. However, a special domain that regulates the close contact between the ER and mitochondria, known as the ...
Yuyan Chen +9 more
semanticscholar +1 more source
Hakuna MAM-Tata: Investigating the role of mitochondrial-associated membranes in ALS.
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2023 Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease leading to selective and progressive motor neuron (MN) death. Despite significant heterogeneity in pathogenic and clinical terms, MN demise ultimately unifies patients. Across
Anna Fernàndez Bernal +4 more
semanticscholar +1 more source