Results 11 to 20 of about 16,726 (54)

GRP75-faciliated Mitochondria-associated ER Membrane (MAM) Integrity controls Cisplatin-resistance in Ovarian Cancer Patients

International Journal on Biological Sciences, 2022
Background: Control of ER-mitochondrial Ca2+ fluxes is a critical checkpoint to determine cell fate under stress. The 75-kDa glucose-regulated protein (GRP75) is a key tether protein facilitating mitochondria-associated ER membrane (MAM) formation ...
Jing Li, Fangzheng Qi, Huishan Su, Chuanshan Zhang, Qing Zhang, Ying Chen, Ping Chen, Linjia Su, Yanan Chen, Yuqi Yang, Zhesheng Chen, Sihe Zhang   +11 more
semanticscholar   +1 more source

Intraspecific Diversity of Microbial Anti-Inflammatory Molecule (MAM) from Faecalibacterium prausnitzii

International Journal of Molecular Sciences, 2022
The commensal bacterium Faecalibacterium prausnitzii has unique anti-inflammatory properties, at least some of which have been attributed to its production of MAM, the Microbial Anti-inflammatory Molecule. Previous phylogenetic studies of F.
S. Auger, C. Kropp, Esther Borras-Nogues, W. Chanput, G. André-Leroux, Oscar Gitton-Quent, L. Benevides, N. Breyner, V. Azevedo, P. Langella, J. Chatel   +10 more
semanticscholar   +1 more source

Отримання магнітокерованого біосорбенту на основі мікроорганізмів активного мулу

Innovative Biosystems and Bioengineering, 2018
Проблематика. Забруднення стічних вод важкими металами є характерним для багатьох галузей промисловості, і їх видалення є важливим для екологічної безпеки довкілля.
Svitlana Gorobets, Kseniia Hetmanenko, Daryna Ponomarenko, Oleksii Kovalyov, Irina Borovik   +4 more
doaj   +1 more source

Overexpression of MFN2 alleviates sorafenib-induced cardiomyocyte necroptosis via the MAM-CaMKIIδ pathway in vitro and in vivo

Theranostics, 2022
Background: The continued success of oncological therapeutics is dependent on the mitigation of treatment-related adverse events, particularly cardiovascular toxicities.
Zi-xuan Song, Hai-xu Song, Dan Liu, Bingju Yan, Daowen Wang, Yan Zhang, Xiaojie Zhao, X. Tian, Chenghui Yan, Yaling Han   +9 more
semanticscholar   +1 more source

Виявлення продуцентів біогенних магнітних наночастинок серед представників грибів відділів аскоміцети (Ascomycota) і базидіоміцети (Basidiomycota)

Innovative Biosystems and Bioengineering, 2018
Проблематика. Біогенні магнітні наночастинки (БМН) виявлено у представників усіх трьох надцарств живих організмів: бактерій, архей та еукаріотів. При цьому вcтановлено, що механізм біомінералізації БМН єдиний для всіх живих організмів.
Svitlana Gorobets, Oksana Gorobets, Iryna Kovalchuk, Liubov Yevzhyk   +3 more
doaj   +1 more source

Біоінформаційне виявлення продуцентів магнітних наночастинок серед залізо- і марганецьокисних бактерій

Innovative Biosystems and Bioengineering, 2018
Проблематика. В Україні понад 17 % підземних водозаборів відносяться до некондиційних за вмістом заліза та 4,4 % – за вмістом марганцю. Підвищений вміст цих елементів спричиняє погіршення органолептичних властивостей питної води, призводить до утворення ...
Svitlana Gorobets, Oleksandr Kravchenko, Maryna Bulaievska, Olena Panchenko   +3 more
doaj   +1 more source

Intermittent Hypoxia-Induced Cardiomyocyte Death Is Mediated by HIF-1 Dependent MAM Disruption

Antioxidants, 2022
Rationale: Intermittent hypoxia (IH) is one of the main features of sleep-disordered breathing (SDB). Recent findings indicate that hypoxia inducible factor-1 (HIF-1) promotes cardiomyocytes apoptosis during chronic IH, but the mechanisms involved remain
Sophie Moulin, Amandine Thomas, S. Wagner, M. Arzt, H. Dubouchaud, F. Lamarche, S. Bouyon, G. Vial, D. Godin-Ribuot, J. Pépin, C. Arnaud, E. Belaidi   +11 more
semanticscholar   +1 more source

Attribute Analytics Performance Metrics from the MAM Consortium Interlaboratory Study

Journal of the American Society for Mass Spectrometry, 2022
The multi-attribute method (MAM) was conceived as a single assay to potentially replace multiple single-attribute assays that have long been used in process development and quality control (QC) for protein therapeutics.
Trina Mouchahoir, John E. Schiel, Richard S. Rogers, A. Heckert, B. Place, Aaron Ammerman, Xiaoxiao Li, Tom Robinson, Brian Schmidt, Chris M Chumsae, Xinbi Li, Anton V. Manuilov, Bo Yan, G. Staples, Da Ren, Alexander J. Veach, Dongdong Wang, W. Yared, Z. Sosic, Yan Wang, Li Zang, Anthony Leone, Peiran Liu, R. Ludwig, L. Tao, Wei Wu, A. Cansizoglu, A. Hanneman, Greg W Adams, Irina Perdivara, Hunter Walker, Margo E. Wilson, A. Brandenburg, Nick DeGraan-Weber, S. Gotta, J. Shambaugh, Melissa Alvarez, X. C. Yu, Li Cao, Chun-hong Shao, A. Mahan, Hirsh Nanda, Kristen Nields, N. Nightlinger, Ben Niu, Jihong Wang, Wei Xu, Gabriella Leo, Nunzio Sepe, Yanhong Liu, Bhumit A. Patel, D. Richardson, Yi Wang, Daniela Tizabi, O. Borisov, Yali Lu, E. Maynard, A. Gruhler, K. Haselmann, T. Krogh, C. Sönksen, S. Letarte, Sean Shen, Kristin Boggio, Keith Johnson, Wenqin Ni, Himakshi Patel, D. Ripley, J. Rouse, Ying Zhang, Carly L. Daniels, Andrew W Dawdy, O. Friese, Thomas W. Powers, Justin B Sperry, J. Woods, Eric Carlson, K. Sen, S. Skilton, M. Busch, Anders Lund, M. Stapels, Xuan Guo, S. Heidelberger, H. Kaluarachchi, S. Mccarthy, John Kim, Jing Zhen, Ying Zhou, S. Rogstad, Xiaoshi Wang, Jing Fang, Weibin Chen, Y. Yu, J. G. Hoogerheide, Rebecca Scott, Hua Yuan   +96 more
semanticscholar   +1 more source

TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis

Cell Death and Disease, 2021
In this work, we have explored the subcellular localization of Bcl2, a major antiapoptotic protein. In U251 glioma cells, we found that Bcl2 is localized mainly in the ER and is translocated to MAM and mitochondria upon induction of apoptosis; this ...
L. Lalier, V. Mignard, M. Joalland, D. Lanoé, P. Cartron, S. Manon, F. Vallette   +6 more
semanticscholar   +1 more source

New Peak Detection Performance Metrics from the MAM Consortium Interlaboratory Study.

Journal of the American Society for Mass Spectrometry, 2021
The Multi-Attribute Method (MAM) Consortium was initially formed as a venue to harmonize best practices, share experiences, and generate innovative methodologies to facilitate widespread integration of the MAM platform, which is an emerging ultra-high ...
Trina Mouchahoir, John E. Schiel, Richard S. Rogers, A. Heckert, B. Place, Aaron Ammerman, Xiaoxiao Li, Tom Robinson, Brian Schmidt, Chris M Chumsae, Xinbi Li, Anton V. Manuilov, Bo Yan, G. Staples, Da Ren, Alexander J. Veach, Dongdong Wang, Wael Yared, Z. Sosic, Yan Wang, Li Zang, A. Leone, Peiran Liu, R. Ludwig, L. Tao, Wei Wu, A. Cansizoglu, A. Hanneman, Greg W Adams, Irina Perdivara, Hunter Walker, Margo I. Wilson, A. Brandenburg, Nick DeGraan-Weber, S. Gotta, J. Shambaugh, Melissa Alvarez, X. C. Yu, Li Cao, Chun-hong Shao, Andrew D. Mahan, Hirsh Nanda, Kristen Nields, N. Nightlinger, H. Barysz, M. Jahn, Ben Niu, Jihong Wang, Gabriella Leo, Nunzio Sepe, Yan-Hui Liu, Bhumit A. Patel, D. Richardson, Yi Wang, Daniela Tizabi, O. Borisov, Yali Lu, E. Maynard, A. Gruhler, K. Haselmann, T. Krogh, C. Sönksen, S. Letarte, Sean Shen, K. Boggio, Keith Johnson, Wenqin Ni, Himakshi Patel, David Ripley, J. Rouse, Ying Zhang, Carly L. Daniels, Andrew W Dawdy, O. Friese, Thomas W. Powers, Justin B Sperry, J. Woods, Eric Carlson, K. Sen, S. Skilton, M. Busch, Anders Lund, M. Stapels, Xuan Guo, S. Heidelberger, H. Kaluarachchi, S. McCarthy, John Kim, Jing Zhen, Ying Zhou, S. Rogstad, Xiaoshi Wang, Jing Fang, Weibin Chen, Y. Yu, J. G. Hoogerheide, Rebecca Scott, Hua Yuan   +97 more
semanticscholar   +1 more source