Results 41 to 50 of about 16,726 (54)

There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases

Trends in Neurosciences, 2016
Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis with associated frontotemporal dementia (ALS/FTD) are major neurodegenerative diseases for which there are no cures.
Sébastien Paillusson, R. Stoica, P. Gomez-Suaga, Dawn H. W. Lau, Sarah Mueller, Tanya Miller, Christopher C. J. Miller   +6 more
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DsbA-L ameliorates high glucose induced tubular damage through maintaining MAM integrity

EBioMedicine, 2019
Background The mitochondrial associated endoplasmic reticulum (ER) membrane (MAM) provides a platform for communication between the mitochondria and ER, and it plays a vital role in many biological functions. Disulphide-bond A oxidoreductase-like protein
Ming Yang, Li Zhao, Peng Gao, Xuejing Zhu, Yachun Han, Xianghui Chen, Li Li, Ying Xiao, Ling Wei, Chenrui Li, Li Xiao, Shuguang Yuan, Fuyou Liu, Lily Q. Dong, Y. Kanwar, Lin Sun   +15 more
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Microbial Anti-Inflammatory Molecule (MAM) from Faecalibacterium prausnitzii Shows a Protective Effect on DNBS and DSS-Induced Colitis Model in Mice through Inhibition of NF-κB Pathway

Frontiers in Microbiology, 2017
Faecalibacterium prausnitzii and its supernatant showed protective effects in different chemically-induced colitis models in mice. Recently, we described 7 peptides found in the F. prausnitzii supernatant, all belonging to a protein called Microbial Anti-
N. Breyner, C. Michon, Cassiana S. de Sousa, Priscilla C B Vilas Boas, F. Chain, V. Azevedo, P. Langella, J. Chatel   +7 more
semanticscholar   +1 more source

IITC-MAM 2023 Sponsorship

2023 IEEE International Interconnect Technology Conference (IITC) and IEEE Materials for Advanced Metallization Conference (MAM)(IITC/MAM), 2023

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Disruption of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Contributes to Muscle Insulin Resistance in Mice and Humans

Diabetes, 2018
E. Tubbs, S. Chanon, Maud Robert, N. Bendridi, G. Bidaux, M. Chauvin, Jingwei Ji-cao, Christine Durand, Daphné Gauvrit-Ramette, H. Vidal, E. Lefai, J. Rieusset   +11 more
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The Wolfram-like variant WFS1E864K destabilizes MAM and compromises autophagy and mitophagy in human and mice

bioRxiv, 2023
Dominant variants in WFS1, a gene coding for the mitochondria-associated endoplasmic reticulum (ER) membrane (MAM) resident protein Wolframin, have been associated with Wolfram-like syndrome (WLS). In vitro and in vivo, WFS1 loss results in reduced ER to
S. Patergnani, Méghane S. Bataillard, A. Danese, Stacy Alves, Chantal Cazevieille, René Valéro, L. Tranebjærg, Tangui Maurice, P. Pinton, B. Delprat, Elodie M. Richard   +10 more
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Ferulic acid attenuates high glucose-induced MAM alterations via PACS2/IP3R2/FUNDC1/VDAC1 pathway activating proapoptotic proteins and ameliorates cardiomyopathy in diabetic rats.

International Journal of Cardiology, 2022
BACKGROUND Diabetic cardiomyopathy (DCM) is one of the severe complications of diabetes with no known biomarkers for early detection. Mitochondria-associated endoplasmic reticulum membranes (MAM) are less studied subcellular targets but an emerging area ...
P. Salin Raj, Anupama Nair, M. R. Preetha Rani, K. Rajankutty, S. Ranjith, K. Raghu   +5 more
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Novel reporters of mitochondria‐associated membranes (MAM), MAMtrackers, demonstrate MAM disruption as a common pathological feature in amyotrophic lateral sclerosis

The FASEB Journal, 2021
The mitochondria‐associated membrane (MAM) is a functional subdomain of the endoplasmic reticulum membrane that tethers to the mitochondrial outer membrane and is essential for cellular homeostasis.
Shohei Sakai, Seiji Watanabe, O. Komine, Akira Sobue, Koji Yamanaka   +4 more
semanticscholar   +1 more source

Sulforaphane Balances Ca2+ Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).

Molecular Nutrition & Food Research, 2021
SCOPE Mitochondria-associated membrane (MAM) connecting endoplasmic reticulum (ER) and mitochondria plays a significant role in lipid metabolism and Ca2+ homeostasis.
Sicong Tian, Peng Lei, Jing Zhang, Yao Sun, Baolong Li, Yujuan Shan   +5 more
semanticscholar   +1 more source

Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS)

Nature Communications
Mitochondrial function is modulated by its interaction with the endoplasmic reticulum (ER). Recent research indicates that these contacts are disrupted in familial models of amyotrophic lateral sclerosis (ALS).
D. Larrea, K. Tamucci, K. Kabra, K. Velasco, T. Yun, M. Pera, J. Montesinos, R.R. Agrawal, C. Paradas, John W Smerdon, Emily R. Lowry, Anna Stepanova, B. Yoval-Sánchez, Alexander Galkin, H. Wichterle, E. Area-Gómez   +15 more
semanticscholar   +1 more source