Results 51 to 54 of about 16,726 (54)

Mitochondrial associated ER membrane (MAM) compartment and its dysregulation in Amyotrophic lateral sclerosis (ALS).

Seminars in Cell and Developmental Biology, 2021
The endoplasmic reticulum (ER) and mitochondria connect at multiple contact sites to form a unique cellular compartment, termed the 'mitochondria-associated ER membranes' (MAMs).
S. Parakh, J. Atkin
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Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment.

Biochemical Pharmacology, 2020
Gestational methylazoxymethanol acetate (MAM) treatment produces offspring with adult phenotype relevant to schizophrenia, including positive- and negative-like symptoms, cognitive deficits, dopaminergic dysfunction, structural and functional ...
T. Stark, M. Di Bartolomeo, Roberta Di Marco, E. Dražanová, C. Platania, F. Iannotti, J. Ruda-Kucerova, C. D'Addario, L. Krátká, V. Pekarik, F. Piscitelli, Z. Babinská, J. Fedotova, G. Giurdanella, S. Salomone, A. Šulcová, C. Bucolo, C. Wotjak, Z. Starčuk, F. Drago, R. Mechoulam, V. Di Marzo, V. Micale   +22 more
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2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1).

Free Radical Biology & Medicine, 2020
Glioblastoma (GBM) are the most malignant brain tumors in humans and have a very poor prognosis. Temozolomide (TMZ), the only chemotherapeutic drug for GBM treatment, induced apoptosis but frequently developed resistance.
Jie Yu, Bingling Zhong, Long Jin, Ying Hou, Nana Ai, W. Ge, Luoxiang Li, Shuqin Liu, Jin-jian Lu, Xiuping Chen   +9 more
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Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia

Neuropharmacology, 2019
In agreement with the neurodevelopmental hypothesis of schizophrenia, prenatal exposure of rats to the antimitotic agent methylazoxymethanol acetate (MAM) at gestational day 17 produced long‐lasting behavioral alterations such as social withdrawal and ...
T. Stark, J. Ruda-Kucerova, F. Iannotti, C. D'Addario, Roberta Di Marco, V. Pekarik, E. Dražanová, F. Piscitelli, M. Bari, Z. Babinská, G. Giurdanella, M. Di Bartolomeo, S. Salomone, A. Šulcová, M. Maccarrone, C. Wotjak, Z. Starčuk, F. Drago, R. Mechoulam, V. Di Marzo, V. Micale   +20 more
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