Results 81 to 90 of about 68,004 (267)

Fine Scale Phylogeography of Urban Western European Hedgehog Erinaceus europaeus in South‐East England

open access: yesEcology and Evolution
Preserving genetic diversity within species and populations is an important conservation goal, yet observed genetic structure can be influenced by both contemporary and historical processes. Here, we investigate the phylogeography of the western European
Jessica Turner   +4 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Research Note. Trichinella spiralis parasitizing Puma concolor: first record in wildlife in Chile

open access: yesHelminthologia, 2015
The genus Trichinella is widespread in all continents but Antarctica. The only way to identify the species/genotypes is through molecular analyses. In Chile, only one study has reported Trichinella larvae in a cougar, but the species of Trichinella was ...
Landaeta-Aqueveque C.   +7 more
doaj   +1 more source

Mammal Skin

open access: yes, 1982
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
openaire   +2 more sources

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

A leucistic female Canis latrans (Carnivora: Canidae) in Costa Rica

open access: yesCuadernos de investigación UNED, 2019
Partial depigmentation (leucism) is rare in mammals. We report 17 camera trap records of a single female leucistic coyote (Canis latrans) in Costa Rica between 2014 and 2018.
Stephanny Arroyo Arce   +5 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

L'homme et les mammifères de France métropolitaine : évolution historique et introductions d'espèces dans les milieux humides et aquatiques

open access: yesKnowledge and Management of Aquatic Ecosystems, 1997
De par ses activités diversifiées, l'homme a modifié en permanence la faune mammalienne de France métropolitaine. Responsable de certaines extinctions, il est également à l'origine de réintroductions d'espèces autochtones et d'introductions d'espèces ...
MAURIN H., GAVAZZI E.
doaj   +1 more source

Constructing Mammal Occurrence Status and Deep Learning Training Data from Camera Trap Surveys in Wind Farm [PDF]

open access: yesGeo Data
In South Korea, there has been an increase in the development of onshore wind farms as part of national strategies to achieve carbon neutrality. However, concerns have been raised regarding the potential ecological impacts on terrestrial mammals posed by
Dong-Joo Kim   +4 more
doaj   +1 more source

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