Études d'ingénierie du ribozyme VS de Neurospora [PDF]
, 2015 Les ribozymes sont des ARN catalytiques fréquemment exploités pour le développement d’outils biochimiques et d’agents thérapeutiques. Ils sont particulièrement intéressants pour effectuer l’inactivation de gènes, en permettant la dégradation d’ARNm ou
Lacroix-Labonté, Julie
core
Études structurales par résonance magnétique nucléaire du ribozyme VS de Neurospora [PDF]
, 2015 Le ribozyme VS de Neurospora catalyse des réactions de clivage et de ligation d’un lien phosphodiester spécifique essentielles à son cycle de réplication. Il est formé de six régions hélicales (I à VI), qui se divisent en deux domaines, soit le substrat (
Bonneau, Éric
core
Many facets of CPEB proteins in neurons and beyond: expression, mRNA recognition and phosphorylation [PDF]
CPEBs are a family of evolutionary conserved auxiliary translational factors. They bind to CPEs in the 3’UTR of target mRNA and, by interacting with other members of the translational machinery, promote or decrease gene expression.
Kaczmarczyk, Lech
core
B2 and ALU retrotransposons are self-cleaving ribozymes whose activity is enhanced by EZH2. [PDF]
Proc Natl Acad Sci U S A, 2020 Hernandez AJ +5 more
europepmc +1 more source
Influence of a 3' Terminal Ribozyme on AgoshRNA Biogenesis and Activity. [PDF]
Mol Ther Nucleic Acids, 2019 Herrera-Carrillo E, Gao Z, Berkhout B.
europepmc +1 more source
Inhibition of Cpeb3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs and enhances object location memory. [PDF]
ElifeChen CC +11 more
europepmc +1 more source
Minimal twister sister-like self-cleaving ribozymes in the human genome revealed by deep mutational scanning. [PDF]
ElifeZhang Z +5 more
europepmc +1 more source
CHiTA: A scarless high-throughput pipeline for characterization of ribozymes. [PDF]
MethodsMcKinley LN, Bevilacqua PC.
europepmc +1 more source
Novel ribozymes: discovery, catalytic mechanisms, and the quest to understand biological function. [PDF]
Nucleic Acids Res, 2019 Weinberg CE, Weinberg Z, Hammann C.
europepmc +1 more source