Charakterisierung des CPEB3 Ribozyms : Studien zur Aufklärung des Mechanismus eines humanen Ribozyms [PDF]
Kurze RNA Stränge mit enzymatischer Aktivität sind als Ribozyme bekannt. Das HDV-ähnliche CPEB3 Ribozym ist eine wenig erforschte selbstspaltende RNA. Es existiert in einer einzelnen hochkonservierten Kopie in der Sequenz des zweiten Introns im cpeb3 Gen
Kulikov, Katharina
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Rapid discovery of functional RNA domains. [PDF]
Many strategies have been implemented to enrich an RNA population for a selectable function, but demarcation of the optimal functional motifs or minimal structures within longer libraries remains a lengthy and tedious process.
Cole, Kyle +3 more
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Conformational dynamics in the disordered region of human CPEB3 linked to memory consolidation. [PDF]
BMC Biol, 2022 Ramírez de Mingo D +4 more
europepmc +1 more source
Investigating and expanding the functionality of RNA catalysts: Studies of the hepatitis delta virus, the hammerhead, and the aminoacyl-tRNA synthetase-like ribozymes [PDF]
, 2016 Ribozymes, just like protein enzymes, catalyze diverse chemical reactions. The first goal of this dissertation is to understand the mechanism of ribozyme-mediated phosphodiester cleavage reaction.
Chen, Ji
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Functional Roles of Chelated Magnesium Ions in RNA Folding and Function. [PDF]
Biochemistry, 2021 Yamagami R, Sieg JP, Bevilacqua PC.
europepmc +1 more source
Ribozimas tipo Hairpin en el genoma de arroz revelan una antigua integración de un satélite viral de RNA [PDF]
, 2017 [EN] Catalytic RNAs or ribozymes are considered survivors o f an hypothetic pre - biotic RNA world that would ha ve remained conserved in today organisms’ genomes.
Contreras Garrido, Adrián Antonio
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Rock, scissors, paper: How RNA structure informs function. [PDF]
Plant Cell, 2023 Assmann SM, Chou HL, Bevilacqua PC.
europepmc +1 more source
Unraveling Aspects of Community Structure in Microbiomes – From Small Ribozymes to Global Ecological Trends [PDF]
Microorganisms fulfill crucial roles in all aspects of life, ranging from global biochemical nutrient cycling to human health and disease. Recent advances in sequencing, bioinformatic tools and databases make it possible to better investigate uncultured ...
Malfertheiner, Lukas
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A Story of Growing Confusion: Genes and Their Regulation [PDF]
, 2018 High-throughput experiments have produced convicing evidence for an extensive contribution of diverse classes of RNAs in the expression of genetic information.
Prohaska, Sonja J., Stadler, Peter F.
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Análisis de RNAs catalíticos en retroelementos de plantas [PDF]
, 2018 Self-cleaving ribozymes such as the hammerhead (HHR), the hepatitis-¿ (HDV) or the twister (Tw) motifs, are a group of small catalytic RNAs with a numerous and widespread occurrence in the genomes of organisms from all domains of life.
Martín Guindal, Andrea
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