Results 71 to 80 of about 81,507 (288)

High glucose enhances store-operated calcium entry by upregulating ORAI/STIM via calcineurin-NFAT signalling [PDF]

, 2014
© 2014, Springer-Verlag Berlin Heidelberg. Abstract: ORAI and stromal interaction molecule (STIM) are store-operated channel molecules that play essential roles in human physiology through a coupling mechanism of internal Ca 2+ store to Ca 2+ influx ...
Atkin, Stephen L., Ayoola, James, Berglund, Lisa,, Bhandari, Sunil, Chen, Gui-Lan, Daskoulidou, Nikoleta, Gomez, Maria,, Griffin, Steven, Jiang, Hongni, Kotova, Olga,, Lund University., Lund University., Lund University., Xu, Shang-Zhong, Zeng, Bo   +14 more
core   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

A direct comparison of decision rules for early discharge of suspected acute coronary syndromes in the era of high sensitivity troponin [PDF]

, 2018
Background: We tested the hypothesis that a single high sensitivity troponin at limits of detection (LOD HSTnT) (<5 ng/l) combined with a presentation non-ischaemic electrocardiogram is superior to low-risk Global Registry of Acute Coronary Events ...
Albouaini, Khaled, Chew, Pei Gee, Dodd, James, Fisher, Michael, Frost, Fredrick, Grainger, Ruth, Jones, Julia, Khand, Aleem, Kunadian, Babu, Mullen, Liam, Obafemi, Toba, Patel, Bilal, Rawatl, Anju, Tong, Sarah, Velavan, Periaswamy, Zadeh, Heidar   +15 more
core   +1 more source

Capture of isoflurane from anaesthetised dogs and cats following methadone, medetomidine and ketamine administration

Veterinary Record, EarlyView.
Abstract Background Volatile anaesthetic agents contribute to climate change, and reducing this impact is a commendable ambition. We evaluated the efficiency of a veterinary capture device for isoflurane (VET‐can/VET‐dock, SageTech Veterinary) in anaesthetised cats and dogs.
Florence Hillen, David Yates, Kate White
wiley   +1 more source

Total arterial myocardial revascularization in octogenarians

Advances in Interventional Cardiology, 2020
According to the current ESC/EACTS Myocardial Revascularization Guidelines, the left internal mammary artery (LIMA) should always be implanted to graft the left anterior descending (LAD) artery, but an additional arterial graft should be considered in ...
Anna Kędziora, Janusz Konstanty-Kalandyk, Radosław Litwinowicz, Piotr Mazur, Bartłomiej Guzik, Krzysztof Bryniarski, Jacek Piątek   +6 more
doaj   +1 more source

Autologous microsurgical breast reconstruction and coronary artery bypass grafting: an anatomical study and clinical implications [PDF]

, 2012
OBJECTIVE: To identify possible avenues of sparing the internal mammary artery (IMA) for coronary artery bypass grafting (CABG) in women undergoing autologous breast reconstruction with deep inferior epigastric artery perforator (DIEP) flaps. BACKGROUND:
A Marchac, A Mislowsky, A Momeni, A Zulli, AF Hemphill, AH Schwabegger, AJ Cohen, AK Arrington, Alberto Alonso-Burgos, AM Calafiore, AM Calafiore, AM Munhoz, AW Pick, BF Buxton, BH Walpoth, BW Lytle, BW Lytle, C Desantis, CC Stucky, CJ Salgado, CL Dupin, CL Dupin, CL Temple, CM Darcy, CM Malata, CR Correa, CT Khoo, D Atisha, DP Taggart, DP Taggart, E Berreklouw, E Han, EG Tutor, EL Hannan, FD Loop, FI Tarr, GD Rosson, GI Taylor, GL Robb, HK Moon, Iain S. Whitaker, J Cameron, J Cremer, J Ferlay, J Mohebali, J Tatoulis, J Tatoulis, JB Albertengo, JC Selber, JC Selber, JD Schmitto, JF Sabik III, JG Apostolides, JG Nes Van, JL Frodel, JL Kaplan, JL Patnaik, JM Serletti, JM Serletti, John Goldblatt, JS Eom, K Frischknecht, K Ueda, K Yao, KE Follmar, LA Lantieri, LB Puig, LJ Feng, LM Stevens, M Bonacchi, M Bonacchi, M Enajat, M Gwozdziewicz, M Hamdi, M Marín-Gutzke, M Saint-Cyr, M Saint-Cyr, M Schmidt, M Tachi, M Zenati, MA Deja, MA Kerr-Valentic, Mark W. Ashton, MC Park, MJ Black, MJ Hooning, MJ Rees, MM Ninković, MR Movahed, MW Clemens, MY Nahabedian, MY Nahabedian, N Ishikawa, N Trehan, ND Desai, NV Tran, O Heymans, O Villafane, P Achouh, P Kurlansky, P Shah, PA Hayward, PB Garvey, Pedro L. Guio-Aguilar, PG Cordeiro, PN Blondeel, PW Boonstra, R Ali, RJ Dotson, RJ Greer-Bayramoglu, RJ Greer-Bayramoglu, RM Haywood, RR Lazzara, S Ahmed, S Goldman, S Kitamura, S Majumder, S Miyamoto, S Miyamoto, S Verma, SH Giordano, SL Moran, SL Spear, SM O’Brien, SR Wise, SS Kroll, SS Kroll, SS Kroll, T Guzzetti, T Higami, T Kinoshita, TH Damen, TM Tuttle, TS Liu, U Livi, Warren M. Rozen, World Health Organization, Xuan Ye, YL Yap, ZM Arnez   +139 more
core   +1 more source

In Vitro and In Vivo Evaluation of Decellularized Porcine Femoral Aorta Reinforced With Electrospun Coarse Polycaprolactone Fibers for Vascular Graft Application

Artificial Organs, EarlyView.
This study aims to develop a hybrid small‐diameter vascular graft by combining electrospun PCL with decellularized porcine femoral aorta (PECM). The graft showed complete decellularization, strong mechanical integrity, and no layer delamination.
Hyun‐Yong Lee, Md. Abdullah Al Fahad, Myeongki Park, Hoe‐Jin Kang, Nusrat Jahan, Prayas Chakma Shanto, Hyeyoung Kim, Byong‐Taek Lee, Sang Ho Bae   +8 more
wiley   +1 more source

Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention

ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou, Yu Wu, Guoran Li, Yongwen Qin, Man Qi, Zhitao Jin   +5 more
wiley   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells [PDF]

, 2008
Purinergic signalling is important both in short-term control of vascular tone and in longer-term control of cell proliferation, migration and death involved in vascular remodelling.
Burnstock, G
core