Results 111 to 120 of about 142,576 (312)
Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases
Animal Models and Experimental Medicine, EarlyView.Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam +4 more
wiley +1 more source
, 2011 Background Information about the effects of unsaturated fatty acids (UFA) supplementation on the health and integrity of the mammary gland in lactating dairy cows is lacking.
Kruijt, L. +4 more
core +1 more source
Development of immunocompetent models for primary and metastatic ER+ breast cancer
Animal Models and Experimental Medicine, EarlyView.This study explores syngeneic, immunocompetent models of ER+ breast cancer in 129S6/SvEv mice, using trackable tumor cells to model both primary tumors and metastasis. The models show promise, while also revealing limitations for studying advanced disease and immune interactions.
Devon M. Bull +5 more
wiley +1 more source
SINGLE CELL TRANSCRIPTOMIC ANALYSES OF HUMAN MAMMARY GLAND AND BREAST TUMORS [PDF]
, 2022 openBreast cancer is the most frequently diagnosed cause of death from cancer in women world-wide, and the second cause of death from cancer in women in developed countries.
OTTAVIANO, CATERINA
core
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Evaluation of the expression of matrix metalloproteinase 9 and neutrophil gelatinase associated lipocalin in serum, urine and tumoral tissues of female dogs suffering from mammary gland tumors [PDF]
, 2013 In human medicine, it has been shown recently that the level of expression of matrix metalloproteinase-9 (MMP-9) and neutrophil gelatinase-associated lipocalin (NGAL) in serum, urine, and breast tissue were significantly increased in patients with breast
Belot, Guillaume
core
Animal Research and One Health, EarlyView.The effects of restricted nursing (RN) and the administration of a bovine appeasing substance (BAS) on days −8 and 0 in relation to weaning were evaluated. Both strategies were effective in improving the growth performance of beef calves. Regarding welfare, BAS ‐especially on day 0‐ was more effective than RN.
Denise E. Mussalafo +8 more
wiley +1 more source
BMC Cancer, 2008 Background Genetically engineered mouse models of mammary gland cancer enable the in vivo study of molecular mechanisms and signaling during development and cancer pathophysiology.
Cotarla Ion +5 more
doaj +1 more source
A Transgenic MMTV-Flippase Mouse Line for Molecular Engineering in Mammary Gland and Breast Cancer Mouse Models. [PDF]
, 2019 Genetically engineered mouse models have become an indispensable tool for breast cancer research. Combination of multiple site-specific recombination systems such as Cre/loxP and Flippase (Flp)/Frt allows for engineering of sophisticated, multi-layered ...
Christofori, Gerhard +5 more
core +1 more source
Animal Research and One Health, EarlyView.The bioactive substances we extracted from Lycium barbarum residue (LBR) have a typical polysaccharide structure. When 1.80% LBR was used to replace maize in the diet, the average daily gain of rossbred Simmental was significantly increased, and anti‐inflammatory ability was improved. In addition, LBR improved the fecal microbial composition, increased
Kun Cai +10 more
wiley +1 more source