Results 211 to 220 of about 13,812 (297)

Comparative analysis of TP53 gene in Tupaia belangeri subspecies (Tupaia belangeri yaoshanensis vs. Tupaia belangeri chinensis) and identification of mutations in spontaneous tumor cases

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study provides the first evidence of natural TP53 variation between tree shrew subspecies and identifies somatic TP53 mutations in spontaneous tree shrew sarcomas. The high structural and functional conservation of tree shrew p53 with humans supports its utility as a relevant model for TP53‐related cancer research.
Yingying Cao   +4 more
wiley   +1 more source

Gold Clusters With Open‐Shell Ligands: Superatom Mediated Magnetic Interaction

open access: yesAngewandte Chemie, EarlyView.
Open‐shell verdazyl radicals were covalently integrated with atomically precise Ir‐doped Au12 (Ir@Au12) superatoms. The resulting radical–superatom hybrids exhibit photoinduced electron transfer, spin delocalization onto the metal‐cluster core, and weak ferromagnetic communication between radicals mediated by the superatomic electronic structure ...
Katsuya Mutoh   +7 more
wiley   +2 more sources

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

open access: yesAnnals of Neurology, EarlyView.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato   +7 more
wiley   +1 more source

Prophage Activation Triggers Extracellular Synthesis of DNA in Bacterial Biofilms via Rolling Circle Replication

open access: yesAngewandte Chemie, EarlyView.
Shewanella oneidensis and Bacillus subtilis, both harboring prophages, reveal a novel biosynthetic route to scalable and programmable DNA superstructures in flower‐ and wire‐like shapes, respectively. Activation of prophages is achieved via 3‐hour starvation and monitored using reporter strains.
Gabriel Antonio S. Minero   +7 more
wiley   +2 more sources

Rewilding: history, intervention and the quest for immanence. [PDF]

open access: yesHist Philos Life Sci
Valverde Pérez N, Castro García Ò.
europepmc   +1 more source

Polyproline: A Synthetic Polypeptide With Unique Properties

open access: yesAngewandte Chemie, EarlyView.
Poly‐L‐proline is a unique polypeptide distinguished by its well‐defined secondary structures and unusual thermal behavior. This mini review highlights recent advances in the synthesis of poly‐L‐proline by N‐carboxyanhydride (NCA) polymerization, the formation of structurally defined architectures and nanostructures, and emerging strategies that ...
Rosanna Le Scouarnec   +3 more
wiley   +2 more sources

Analysis of Training Behavior in Users of a Fitness App: Cross-Sectional Study. [PDF]

open access: yesJMIR Mhealth Uhealth
Fuente-Vidal A   +7 more
europepmc   +1 more source

Long-Term Discharge Records from United States and European Karst Springs: Data Limitations in Trend Analysis. [PDF]

open access: yesGround Water
Toran L   +7 more
europepmc   +1 more source

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