Results 41 to 50 of about 11,387 (308)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity

Arthritis Care &Research, EarlyView.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

La grotte de Fronsac à Vieux-Mareuil (Dordogne)

Les Nouvelles de l’Archéologie, 2019
The cave of Fronsac is for its several engraved schematic female figures attributed to Upper Magdalenian (Bosinski 2011). A recent monography has inserted the cave back into scientific news (Delluc and Delluc 2013), at the same time we were launching a ...
Patrick Paillet, Elena Paillet, Grégory Dandurand, Peggy Bonnet-Jacquement, Myriam Boudadi-Maligne, Sandrine Costamagno, Mathieu Langlais, Véronique Laroulandie, Alexandre Lefebvre, Jean-Baptiste Mallye   +9 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Hydrothermal Activity in the Southwest Yellowstone Plateau Volcanic Field

Geochemistry, Geophysics, Geosystems, 2020
In the past two decades, the U.S. Geological Survey and the National Park Service have studied hydrothermal activity across the Yellowstone Plateau Volcanic Field (YPVF) to improve the understanding of the magmatic‐hydrothermal system and to provide a ...
S. Hurwitz, R. B. McCleskey, D. Bergfeld, S. E. Peek, D. D. Susong, D. A. Roth, J. D. G. Hungerford, E. B. White, L. N. Harrison, B. Hosseini, R. G. Vaughan, A. G. Hunt, J. B. Paces   +12 more
doaj   +1 more source

Ice and Ivory: the cryopolitics of mammoth de-extinction

Journal of Political Ecology, 2021
Woolly mammoth tusk hunting has become a black-market industry in the Siberian region of Yakutia, where thawing permafrost due to climate change is revealing the bodies of thousands of mammoths.
Charlotte A. Wrigley
doaj   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

A Newly Emerging Thermal Area in Yellowstone

Frontiers in Earth Science, 2020
Yellowstone is a large restless caldera that contains many dynamic thermal areas that are the surface expression of the deeper magmatic system. In 2018, using a Landsat 8 nighttime thermal infrared image, we discovered the emergence of a new thermal area
R. Greg Vaughan, Jefferson D. G. Hungerford, William Keller   +2 more
doaj   +1 more source