Results 111 to 120 of about 24,059,335 (416)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Seek Guidance for Complex Practice Challenges: Ethics, Financial Protection and Employee Relations

open access: yesJournal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Push vs. Pull in Web-Based Network Management [PDF]

open access: yesarXiv, 1998
In this paper, we show how Web technologies can be used effectively to (i) address some of the deficiencies of traditional IP network management platforms, and (ii) render these expensive platforms redundant. We build on the concept of embedded management application, proposed by Wellens and Auerbach, and present two models of network management ...
arxiv  

Ensuring Ethical Dental Care: Obtaining Legal Consent for Nonverbal Adults

open access: yesJournal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

Case Management: a data set of definitions [PDF]

open access: yesarXiv, 2015
Knowledge-intensive processes (KiPs) are becoming increasingly important for organizations with the rise of the knowledge society. Due to their unpredictable and emergent characteristic worklfow management solutions are not suitable to support KiPs.
arxiv  

Performance Pay and Top Management Incentives

open access: yes, 1990
Our estimates of the pay-performance relation (including pay, options, stockholdings, and dismissal) for chief executive officers indicate that CEO wealth changes $3.25 for every $1,000 change in shareholder wealth.
Kevin J. Murphy, M. C. Jensen
semanticscholar   +1 more source

2013 ESH/ESC Guidelines for the management of arterial hypertension

open access: yesBlood Pressure, 2007
Because of new evidence on several diagnostic and therapeutic aspects of hypertension, the present guidelines differ in many respects from the previous ones. Some of the most important differences are listed below: 1.
G. Mancia   +24 more
semanticscholar   +1 more source

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