Results 131 to 140 of about 20,758,202 (342)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Chinese expert consensus on the management of adverse reactions to HER2-targeted antibody-drug conjugates in digestive system cancers (2025 edition)

Zhongguo Linchuang Yixue
Digestive system cancers are very prevalent globally. Among these, human epidermal growth factor receptor 2 (HER2)-positive gastric cancer, colorectal cancer, and cholangiocarcinoma are tumors that require particular attention.
Committee on Antitumor Drug Safety Management, Chinese Society of Clinical Oncology (CSCO) Expert
doaj   +1 more source

Characterization and management of neurological adverse events during immune-checkpoint inhibitors treatment: an Italian multicentric experience

, 2021
Luca Diamanti, Alberto Pïcca, Paola Bini, Matteo Gastaldi, Enrico Alfonsi, Anna Pichiecchio, Eugenia Rota, Roberta Rudà, Francesco Bruno, Veronica Villani, Edvina Galiè, Alberto Vogrig, Mariarosaria Valente, Marco Zoccarato, Valentina Poretto, Bruno Giometto, Carolina Cimminiello, Michele Del Vecchio, Enrico Marchioni   +18 more
openalex   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Drug Management Reviews in District Drug Management Unit and General Hospital [PDF]

, 2009
Drug is one of the essential elements in healthcare that should be effectively and efficiently managed. Following the decentralization in 2001 in Indonesia, drug management has changed in district drug management units and also in District General ...
Handayani, R. S. (Rini), Herman, M. J. (Max), Yuniar, Y. (Yuyun)   +2 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Irrigation management transfer: how to make it work for Africa’s smallholders? [PDF]

Water management / Privatization / Small scale systems / Small holders ...
International Water Management Institute (IWMI).
core  

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Editorial

IIMB Management Review, 2021
Jishnu Hazra, Editor-in-ChiefIIMB Management Review
doaj   +1 more source

Crop variety management for climate adaptation supported by citizen science

, 2019
Jacob van Etten, Kauê de Sousa, Amílcar Aguilar, M. Barrios, A. Coto, Matteo Dell’Acqua, Carlo Fadda, Yosef Gebrehawaryat, Jeske van de Gevel, Arnab Gupta, Afewerki Yohannes Kiros, B. Madriz, P. Mathur, Dejene K. Mengistu, Leida Mercado, Jemal Mohammed, Ambica Paliwal, Mario Enrico Pè, Carlos F. Quirós, Juan Carlos Rosas, Neeraj Sharma, S. Sureshkumar Singh, I. Solanki, Jonathan Steinke   +23 more
openalex   +2 more sources