Results 51 to 60 of about 27,553,888 (337)

Navigating AwDa Compliance: Providing Inclusive Care for Patients with Special Needs

Journal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Positive Communication Reduces Risk and Improves Dental Patient Outcomes

Journal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

A fire suppression model for forested range of the Beverly and Qamanirjuaq herds of caribou

Rangifer, 1996
A fire suppression model was developed for forested winter range of the Beverly and Qamanirjuaq (formerly Kaminuriak) herds of barren-ground caribou (Rangifer tarandus groenlandicus) in north-central Canada.
Donald C. Thomas, The Beverly and Qamanirjuaq Caribou Management Board   +1 more
doaj   +1 more source

Intensive Surveys of Watersheds Contributing to McKinney Falls [PDF]

, 1993
This report uses Waller Creek as an example of an urbanized stream with high levels of fecal coliform colonies in dry weather conditions.Waller Creek Working ...
City of Austin Environmental Resource Management Division
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Qanuq ukua kanguit sunialiqpitigu? (What should we do with all of these geese?) Collaborative research to support wildlife co-management and Inuit self-determination

Arctic Science, 2020
Inuit living in Nunavut have harvested light geese and lived near goose colonies for generations. Inuit knowledge includes important information about light goose ecology and management that can inform co-management and enhance scientific research and ...
Dominique A. Henri, Natalie A. Carter, Aupaa Irkok, Shelton Nipisar, Lenny Emiktaut, Bobbie Saviakjuk, Salliq Project Management Committee, Arviat Project Management Committee, Gita J. Ljubicic, Paul A. Smith, Vicky Johnston   +10 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Understanding the outcome and management of children aged 2–59 months with chest indrawing pneumonia: a study protocol for an observational study in Ethiopia, India, Nigeria, Pakistan, Uganda and Zambia

BMJ Open
Introduction Childhood pneumonia is a leading cause of morbidity and mortality among children aged 2–59 months, particularly in low-income and middle-income countries (LMICs), where healthcare providers face significant challenges in diagnosing and ...
Chest Indrawing Pneumonia Management (CIPAM) Study Group
doaj   +1 more source