Results 51 to 60 of about 19,556,464 (342)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Positive Communication Reduces Risk and Improves Dental Patient Outcomes

Journal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

Qanuq ukua kanguit sunialiqpitigu? (What should we do with all of these geese?) Collaborative research to support wildlife co-management and Inuit self-determination

Arctic Science, 2020
Inuit living in Nunavut have harvested light geese and lived near goose colonies for generations. Inuit knowledge includes important information about light goose ecology and management that can inform co-management and enhance scientific research and ...
Dominique A. Henri, Natalie A. Carter, Aupaa Irkok, Shelton Nipisar, Lenny Emiktaut, Bobbie Saviakjuk, Salliq Project Management Committee, Arviat Project Management Committee, Gita J. Ljubicic, Paul A. Smith, Vicky Johnston   +10 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

SDN management layer: design requirements and future direction [PDF]

, 2014
Computer networks are becoming more and more complex and difficult to manage. The research community has been expending a lot of efforts to come up with a general management paradigm that is able to hide the details of the physical infrastructure and ...
Matta, Ibrahim, Wang, Yuefeng
core   +2 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Haste, Pressure and Staffing Shortages Contribute to Costly Mistakes

Journal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

Understanding the outcome and management of children aged 2–59 months with chest indrawing pneumonia: a study protocol for an observational study in Ethiopia, India, Nigeria, Pakistan, Uganda and Zambia

BMJ Open
Introduction Childhood pneumonia is a leading cause of morbidity and mortality among children aged 2–59 months, particularly in low-income and middle-income countries (LMICs), where healthcare providers face significant challenges in diagnosing and ...
Chest Indrawing Pneumonia Management (CIPAM) Study Group
doaj   +1 more source

Managing time for managers

South African Journal of Business Management, 1981
Although managers are often concerned about their use of time to get more done, there are even more compelling reasons for the effective use of time. Time is important from the perspectives of health, of employee work performance, and of new products. Managers waste time in many ways, including the confusion of activity with results, lack of planning ...
openaire   +4 more sources

CORPORATE SOCIAL RESPONSIBILITY IN ROMANIA [PDF]

The purpose of this paper is to identify the main opportunities and limitations of corporate social responsibility (CSR). The survey was defined with the aim to involve the highest possible number of relevant CSR topics and give the issue a more ...
Georgescu Bogdan, Militaru Gheorghe, Serbanica Daniel   +2 more
core