Results 51 to 60 of about 9,163,206 (266)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
, 2008 Biweekly, May 25, 2007-Sept. 29, 2008.; Weekly, -May 11, 2007.; Electronic coverage as of Sept. 5, 2014: Vol. 3, no. 1 (Jan. 6, 2006)-v. 5, no. 17 (Sept. 29, 2008); "A publication of the Ohio Emergency Management Agency, a division of the Ohio Department
Ohio Emergency Management Agency.
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Boston University School of Management Faculty profiles
, 1990 Profiles of Boston University School of Management faculty (1990/1991)
Boston University School of Management
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The standard for risk management in portfolios, programs, and projects
, 2019 The Standard for Risk Management in Portfolios, Programs, and Projects is an update and expansion upon PMI's popular reference, The Practice Standard for Project Risk ...
Project Management Institute
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Prospects & Challenges of Implementing Knowledge Management System in IT Industry
, 2018 Recent past has seen an epidemic growth in the adoption of strategic information systems. In order to be successful, enterprises are putting in huge investments into implementation of information technology (IT) and knowledge management systems (KMS ...
Iftikhar, Asim; Institute of Business Management +1 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
A guide to the project management body of knowledge: PMBOK guide
, 2013 A Guide to the Project Management Body of Knowledge (PMBOK Guide) Fifth Edition reflects the collaboration and knowledge of working project managers and provides the fundamentals of project management as they apply to a wide range of projects.
Project Management Institute
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source