Results 101 to 110 of about 11,714,240 (349)
Background: Ukrainian refugees fleeing the conflict between Russia and Ukraine may face significant challenges to their physical, psycho-emotional, social, and spiritual wellbeing.
Willian-Jesús Martín-Dorta +11 more
doaj +1 more source
New York City School Decentralization: The Respective Powers of the City Board of Education and the Community School Boards [PDF]
The city of New York constitutes a single school district and the city Board of Education is charged with the general management and control of educational affairs in the city school district. The Board is subject to the plenary powers of the State Board
McGrail, Kenneth R.
core +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Background Youths are particularly at risk of HIV/AIDS because of their high-risk sexual behaviours and low level of perceived vulnerability to the infection.
Garba Danjuma +3 more
doaj +1 more source
Ownership Concentration, Monitoring and Optimal Board Structure [PDF]
The paper analyzes the optimal structure of the board of directors in a firm with a large shareholder sitting on the board. In a one-tier structure the sole board performs all tasks, while in a two-tier structure the management board is in charge of ...
Annalisa Luporini, Clara Graziano
core
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Forty years of Projeto Lontra: Lessons learned and the future of otter-led estuarine conservation [PDF]
Over four decades, Projeto Lontra has pioneered otter-led estuarine conservation in Brazil, generating one of the world’s longest continuous datasets on Lontra longicaudis and its habitats.
Oldemar de Oliveira Carvalho Junior
doaj +3 more sources
Board composition, process, and activism: evidence within American firms [PDF]
This study provided an empirical test of the effects of compositional and process variables on board activism. The attributes examined were functional area knowledge, independence, duality, and effort norms.
Christopher SHOOK +2 more
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source

