Results 121 to 130 of about 11,714,240 (349)

Women Still Greatly Underrepresented on the Top Boards of Large Companies [PDF]

Executive and supervisory boards of large companies in Germany are still dominated by men - to an extraordinary degree. Only 2.5% of all executive board members in the200 largest companies (not including the financial sector) are women, and only 10% of ...
Anita Wiemer, Elke Holst
core  

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

A syndemic perspective to understanding the intersection of self-directed ageism and depression in older adults: structural determinants and policy implications in Africa

Discover Social Science and Health
Africa’s aging population is growing at an unprecedented rate, bringing with it profound social, political, and economic challenges. Underneath this demographic shift lies a silent but widespread issue:self-directed ageism (SDA) -the type of ageism ...
Bet-ini N. Christian, Jane Data Halliday
doaj   +1 more source

Empirical relationship between board characteristics, earnings management, insolvency risk, and corporate social responsibility

Cogent Business & Management
The study aims to investigate the relationship between board characteristics, earnings management, insolvency risk, and corporate social responsibility (CSR).
Hosam Alden Riyadh, Maher A. Al-Shmam, Mohammed Ghanim Ahmed   +2 more
doaj   +1 more source

Analisis Pengaruh Struktur Kepemilikan dan Mekanisme Tata Kelola Perusahaan terhadap Manajemen Laba pada Perusahaan Manufaktur yang terdaftar di Bursa Efek Thailand dan di Bursa Efek Philippine tahun 2009-2013. [PDF]

, 2017
The purpose of this research is to analyze the effect of ownership structure and corporate governance on earnings management in manufacturing companies in Thailand Stock Exchange and in Philippines Stock Exchange.
Husnul Chotimah, Laila
core  

Board gender composition and waste management: cross-country evidence

The British Accounting Review, 2022
Ammar Ali Gull, Muhammad Atif, Nazim Hussain   +2 more
semanticscholar   +1 more source

Board Gender Diversity and Firm Performance: Recent Evidence from Japan

Journal of Risk and Financial Management
Gender diversity is increasingly recognized as a critical element in corporate management. However, existing research on its impact on firm performance demonstrates inconsistency in a global context.
Kangyi Wang, Jing Ma, Chunxiao Xue, Jianing Zhang   +3 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source