Results 71 to 80 of about 5,251,558 (335)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Status of Health Management Education in India: Past, Present, and Future

Frontiers in Public Health, 2019
This article provides a perspective on the evolution of health management education in India, its current state and the way forward. Health management originated in India in response to the administrative needs of the healthcare system, which is now ...
Sunitha Kalangi, Harshad Thakur
doaj   +1 more source

Building professional qualifications as a model of integration and transfer of knowledge [PDF]

, 2013
The multi-faceted nature of transformations that occur in modern business encourages the evolution of concepts, methods and tools of competitiveness, as a result of which, dynamic changes are seen in the theory and practice of management.
Kozielski, Robert
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Total Quality Management Strategy for Improving the Quality of Education at Kolej Universiti Perguruan Ugama Seri Begawan (Empirical Study in the Arabic Language Education Master's Study Program)

Asatiza
This research aims to determine the Total Quality Management (TQM) strategy for improving the quality of education in the Arabic Language Education Master's Study Program at Kolej Universiti Perguruan Ugama Seri Begawan (KUPU SB).
M. Iqbal Firdaus, Muhamad Hani Yusuf, Wahyu Nugroho, Eiffan Fanani   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

SCIENTIFIC AND METHODOLOGICAL, SPIRITUAL AND MORAL GUIDELINES IN MANAGEMENT TRAINING AT THE STATE UNIVERSITY OF MANAGEMENT (PART 2)

Вестник университета, 2020
The article is a continuation of an article of the same name published in the journal “Vestnik Universiteta” № 12 2019. Presented part is devoted to methodological problems, systemic approach in management and development of guidelines in setting ...
A. M. Ljalin, V. A. Persianov, V. I. Korolevskaja   +2 more
doaj   +1 more source

INFORMATION SYSTEM FOR EDUCATIONAL EVALUATION OF UNIVERSITY'S ACADEMIC ACTIVITIES [PDF]

, 2018
The system of academic activities in higher education institutions is a program created to enable students and academic activities to communicate with each other.
ASHOUR, Salim Fathi Salim, Suryono, Suryono, Widodo, Catur Edi   +2 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Information management of university physical education based on adaptive differential evolutionary algorithm [PDF]

, 2023
Hongchun Jia, Song-Bo He
openalex   +1 more source