Results 121 to 130 of about 3,159,903 (327)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Data management in engineering [PDF]

open access: yes
An introduction to computer based data management is presented with an orientation toward the needs of engineering application. The characteristics and structure of data management systems are discussed.
Browne, J. C.
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Project management for engineers

open access: yes, 2016
In recent years we have witnessed a rapid growth in the use of project management methods and tools as a means by which organisations achieve their objectives. Projects drive business in industries as diverse as transportation, pharmaceuticals, banking, and hospitals etc.
openaire   +2 more sources

Recommendations for NASA research and development in artificial intelligence [PDF]

open access: yes
Basic artificial intelligence (AI) research, AI applications, engineering, institutional management, and previously impractical missions enabled by AI are ...
Brown, D. R., Cheeseman, P. C.
core   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

Biomaterials science and surface engineering strategies for dental peri-implantitis management [PDF]

open access: diamond
Ya-Meng Yu   +5 more
openalex   +1 more source

Goddard research and engineering management exercise /GREMEX/ [PDF]

open access: yes
Computer assisted management simulation exercise for training of personnel as project ...
Baker, R. F.
core   +1 more source

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