Results 41 to 50 of about 2,574 (289)

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Family businesses restrict accrual and real earnings management: Case study in Saudi Arabia

open access: yesCogent Business & Management, 2020
This paper investigates accrual earnings management (AEM) and real earnings management (REM) in family businesses (FB) in Saudi Arabia. Current literature indicates that minority rights are confiscated by the controlling shareholders in a business ...
Adeeb Abdulwahab Alhebri   +1 more
doaj   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu   +8 more
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Personalidades vocacionais e processos de carreira na vida adulta Personalidades vocacionales y procesos de carrera en la vida adulta Vocational personalities and career processes in adult life

open access: yesPsicologia em Estudo, 2007
Esta pesquisa abordou a relação entre interesses vocacionais e os processos de comprometimento e entrincheiramento na carreira em diferentes fases da vida.
Mauro de Oliveira Magalhães   +1 more
doaj   +1 more source

Promoting Healthier Drinking: Evidence From a Vignette Experiment on Contextual and Informational Drivers of Dealcoholized Wine Choices

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Growing demand for healthier beverages is driving innovation in the wine sector, with dealcoholized wine emerging as a promising alternative. However, little is known about the contextual conditions under which consumers would choose dealcoholized wine, particularly in countries with strong wine traditions. To fill this gap, this work examines
Giovanna Piracci   +4 more
wiley   +1 more source

Who Is Structurally Able to Participate in the Sustainable Protein Transition and Through What Mechanisms?

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Participation in transitions toward more sustainable protein consumption is driven primarily by sustainability motivation, whereas behavioural capability determines whether intentions translate into action. Despite high awareness among Chinese consumers, gaps persist, indicating that policies must jointly address motivational and practical barriers to ...
Zhihan Li, Toritseju Begho
wiley   +1 more source

The entrenchment strategy of logistics service providers: Towards a sequential cooperation-competition process?

open access: yesJournal of Transport and Supply Chain Management, 2007
The logistics industry has been attracting the attention of researchers in management for several years. Their focus is increasingly on interorganisational relationships between logistics service providers and their customers, examining the modes of ...
Gilles Paché, Pablo Medina
doaj   +1 more source

Employee ownership: A theoretical and empirical investigation of management entrenchment vs. reward management ☆ [PDF]

open access: yes, 2020
Employee ownership is often used not only as a reward management tool but also as an entrenchment mechanism. The literature suggests that good managers use employee ownership as a reward management tool, whereas bad managers implement it for entrenchment,
André Lapied   +3 more
core  

Corporate Social Responsibility Dan Earnings Management: Managerial Entrenchment Sebagai Variabel Moderasi [PDF]

open access: yes, 2021
Penelitian ini bertujuan menguji pengaruh managerial entrenchment terhadap hubungan tanggung jawab sosial perusahaan (CSR) dengan praktik manajemen laba.
Khosasi, Steven, Eriandani, Rizky
core   +1 more source

Home - About - Disclaimer - Privacy