Results 41 to 50 of about 599 (194)

Other title: Capacity development strategy for existing public water supply systems

open access: yes, 2000
application/pdf"This document is a demonstration of how the State of Kansas, Kansas Department of Health and Environment (KDHE) plans to implement a strategy to assist existing public water systems in improving their technical, financial, and managerial (
Kansas. Bureau of Water.
core  

Implantación de un sistema de gestión integrado con las normas ISO/IEC 27001:2013 e ISO/IEC 20000-1:2018 [PDF]

open access: yes, 2020
[ES] La información es un recurso clave para todas las empresas, los sistemas de información cada vez más están expuestos a amenazas, que pueden vulnerar los activos críticos de información, como la pérdida o robo de datos causada por usuarios no ...
Aburto Zamora, Keith Yasira
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Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Catherine Bolczak

open access: yes, 2019
Catherine (Katie) Bolczak is a Principal Information Systems Engineer with The MITRE Corporation. Katie has over 25 years of experience in Federal Aviation Administration (FAA) research, systems engineering, and acquisition, with projects spanning ...
Bolczak, Catherine
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Kansas Public Water Supply Capacity Development Program: Report to the Governor, 2017

open access: yes, 2017
Water system capacity is the ability to plan for, achieve, and maintain compliance with applicable drinking water standards. Capacity consists of three elements: Technical, Financial, and Managerial (TFM). Technical Capacity or capability is the physical
Kansas. Bureau of Water. Public Water Supply Section
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The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

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