Results 31 to 40 of about 29,914 (227)
REGIONAL ANALYSIS OF FINANCIAL RESOURCES INVOLVED IN RESEARCH DEVELOPMENT AND INNOVATION (RDI) SECTOR IN ROMANIA IN THE LAST DECADE –STUDY DONE ON MACROREGIONS [PDF]
Annals of the University of Oradea: Economic Science, 2012 The present paper present a study done on the Financial Resources in Research Development and Innovation (RDI) sector in Romania during 2000-2010 .
NICOLOV MIRELA
doaj
Development of the Marketing Strategy of Mediahost.sk on the Czech Market [PDF]
, 2012 Diplomová práca sa zameriava na vývoj marketingovej stratégie firmy Mediahost.sk na slovenskom trhu. Analyzuje makro a mikro prostredie v IT priemysle, a to najmä so zameraním na webhosting.
Kapičák, Tomáš
core
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Protection of intellectual property rights an Indian perspective [PDF]
, 2010 The objective of this paper is to provide an overview of the Indian Innovation System, IPR system and other related activities such as Judicial System, Enforcement System, and Academic Institutions etc. The paper is based on the existing data and relates
Balamurugan, R., Radhakrisnan, R.
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
An Empirical Study of Institutional Investor and Enterprise Innovation [PDF]
, 2018 Innovation is the driving force of social and economic development, and a decisive factor in enhancing national competitiveness. In recent years, more and more countries have taken innovation to a strategic height. Chinese institutional investors have an
Min, Cheng
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source