Results 71 to 80 of about 2,757,012 (301)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Digital Rights Management: The Librarian’s Guide

open access: yesJournal of the Medical Library Association, 2018
Digital Rights Management: The Librarian’s Guide offers a comprehensive view of how digital rights management (DRM) shapes all kinds of library decision-making regarding acquisition, access, and management of electronic resources.
A. Robin Bowles
doaj   +1 more source

Development of a Community-Based Fishery Management System in Japan [PDF]

open access: yes
The development of Japan's community-based fishery management system is described. Over the past 250 years, three fishery laws were in effect. These fishery laws commonly adopted a fishing rights system as a tool for coastal fisheries management.
Yamamoto, Tadashi
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

CREATING EFFECTIVE MODELS OF VERTICAL INTEGRATED STRUCTURES IN UKRAINE

open access: yesNauka ta progres transportu, 2011
The results of scientific research aimed at development of methodology-theoretical mechanisms of building the effective models of vertically-integrated structures are presented.
D. V. Koliesnikov
doaj  

Whose right to manage? Distribution of property rights affects equity and power dynamics in comanagement

open access: yesEcology and Society, 2018
Rights-based management approaches are being increasingly applied to global fisheries as an alternative to deficiencies associated with centralized or top-down management.
Adam L. Ayers   +2 more
doaj   +1 more source

TURFs and ITQs: Collective vs. Individual Decision Making [PDF]

open access: yes
While most of the attention in the scientific and policy literature on rights-based institutions has been devoted to Individual Transferable Quotas (ITQs), there are alternatives that involve different configurations of use rights.
Cancino, Jose P.   +2 more
core   +1 more source

The Right to Democratic Participation in Labor Unions and the Use of the Hobbs Act to Combat Organized Crime [PDF]

open access: yes, 1989
The author examines corruption within labor unions and the responses to that corruption with the use of two laws, the Labor-Management Reporting and Disclosure Act of 1959 and the Hobbs Act.
Marshall, Leslie
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Legal Implications of Building Use Rights Certificates Without Land Status Information: Consumer Protection and the Responsibility of the National Land Agency

open access: yesBHUMI: Jurnal Agraria dan Pertanahan
: This research examines the legal uncertainties arising from the issuance of Building Use Rights (HGB) certificates on land with Management Rights (HPL) owned by the Special Capital Region of Jakarta.
Rijal Ibnu Sani, Suartini Suartini
doaj   +1 more source

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