Results 81 to 90 of about 2,757,012 (301)
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Theology of Community-Nurturing
Nadiyka Gerbish
doaj +1 more source
Scholarly work on examining how property rights affect incentives for collective action in common-pool resource management has benefited immensely from the property-rights analytical scheme proposed in the seminal work of Schlager & Ostrom (1992).
Pranay Ranjan, Tomas Koontz
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Property rights and management regimes for high-elevation rangelands in Bhutan have evolved over centuries in response to environmental, cultural, and political imperatives.
Karma Tenzing +2 more
doaj +1 more source
AbstractEssentially, digital rights management refers to “trusted exchange of digital information over the Internet in which the user is granted only those privileges granted by the document sender”. Digital rights management systems serve multiple functions, such as access control, usage control, billing, and the pursuit of legal infringements.
openaire +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Rights-Based Management: Conserving Fisheries, Protecting Economies [PDF]
Healthy and plentiful fisheries are not only good for marine ecosystems, but they are critical to the health, employment and prosperity of over a billion people around the world that rely on fisheries for food and jobs.
core
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Voluntary Approaches to Transitioning from Competitive Fisheries to Rights-Based Management: Bringing the Field into the Lab [PDF]
This paper describes a novel experiment designed to examine how rent dissipation may occur in fisheries in which the right to participate is limited and fishermen compete amongst themselves for shares of an exogenous total allowable catch. We demonstrate
Knapp, Gunnar, Murphy, James J.
core +1 more source

