Results 101 to 110 of about 6,516,881 (303)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Database Management Systems: A NoSQL Analysis [PDF]
, 2013 Volume 1 Issue 7 (September ...
Kadebu, P. (Prudence) +1 more
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Managing Risk and Quality of AI in Healthcare: Are Hospitals Ready for Implementation?
Risk Management and Healthcare PolicyArian Ranjbar,1 Eilin Wermundsen Mork,1 Jesper Ravn,1 Helga Brøgger,2 Per Myrseth,2 Hans Peter Østrem,3 Harry Hallock2 1Medical Technology and E-Health, Akershus University Hospital, Lørenskog, Norway; 2Group Research and Development, DNV AS, Høvik ...
Ranjbar A +6 more
doaj
A component-based product line architecture for workflow management systems [PDF]
, 2004 This paper presents a component-based product line for workflow management systems. The process followed to design the product line was based on the Catalysis method. Extensions were made to represent variability across the process.
Barroca, Leonor +3 more
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Growth performance, carcass yield and gait score of Marshal broiler chicken reared on intensive and semi intensive management systems [PDF]
Malaysian Journal of Animal Science, 2017 The rearing system used in highly productive farms is often subjected to harsh criticism, one of the reasons being its failure to provide adequate welfare.
Oluwadiya, B. O. +4 more
doaj
FOLDER3D: A graphical file management system supporting visualisation of file relationships [PDF]
, 2010 The desktop metaphor with its hierarchical structure of folders is the basis of almost all graphical file management systems. Despite this popularity, these systems suffer from several problems, including the restrictiveness of the single inheritance ...
De Schutter, Simon +3 more
core +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source