Results 131 to 140 of about 17,911,676 (308)
Recent years have seen various attempts at conceptualising integrity management within organisations. This chapter focuses on those integrity management models that take a systems approach. This emphasises interconnectedness and requisite variety, as well as the processual and iterative nature of integrity management and the importance of grassroots ...
Maesschalck, Jeroen +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
International Conference on Industry, Engineering, and Management Systems (2009 : Cocoa Beach, Fla.)
, 2009 Digitized and published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, May 2022.The IEMS'09 conference committee: California State University Stanislaus Department of Management, Operations, and ...
International Conference on Industry, Engineering, and Management Systems
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Report of Committee from Associates for Review of Management Information Systems Evening Curriculum
, 1971 Management Information Systems Research Center. (1971). Report of Committee from Associates for Review of Management Information Systems Evening Curriculum.
Management Information Systems Research Center
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Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Expert systems and expert support systems : the next challenge for management
, 1984 "December 1984. -- Revised September 1985.""A version of this paper appears in Sloan management review, Fall 1986, and in The Rise of managerial computing : the best of the Center for Information Systems Research, ... 1986.
Malone, Thomas W. +2 more
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