Results 71 to 80 of about 2,154,315 (317)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Journal of Management & Engineering Integration, v.18, no.1 (Summer)

Published in SOAR: Shocker Open Access Repository by the Wichita State University Libraries Technical Services, August 2025.Copyright of the Journal of Management and Engineering Integration is the property of the Association of Industry, Engineering and
Association for Industry, Engineering and Management Systems (AIEMS)
core   +1 more source

International Conference on Industry, Engineering, and Management Systems (2010 : Cocoa Beach, Fla.)

, 2010
Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, May 2022.The IEMS'10 conference committee: Nael Aly (Conference Co-Chair); Ahmad Elshennawy (Conference Co-Chair); Alfred Petrosky (Program Chair);
International Conference on Industry, Engineering, and Management Systems
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

International Conference on Industry, Engineering, and Management Systems (2013 : Cocoa Beach, Fla.)

, 2013
Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, May 2022.The IEMS'13 conference committee: The Association for Industry, Engineering, & Management Systems (Sponsor); Nael Aly (Conference Co ...
International Conference on Industry, Engineering, and Management Systems
core   +1 more source

Sistemas de gestión en seguridad y salud en el trabajo (SG-SST). Diagnóstico en el sector de la construcción de Manizales

Teuken Bidikay, Revista Latinoamericana de Investigación en Organizaciones Ambiente y Sociedad, 2018
El presente artículo da a conocer los resultados de un estudio cuyo objetivo general fue establecer el grado de cumplimiento en la implementación del Sistema de Gestión en Seguridad y Salud en el Trabajo (SG-SST) en su componente de Seguridad en el ...
Diana María Roa Quintero, Martín Alonso Pantoja Ospina, Amparo Zapata Gómez   +2 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Production and Economic Characteristics of Intensive and Semi- Intensive Dairy Cattle Management Systems in Vegetable Based Farming System in Welimada, Sri Lanka

Tropical Agricultural Research, 2011
The objective of this study was to identify and compare different dairy cattle management systems in vegetable based farming system in Welimada division in Badulla district (up country wet and intermediate zones) with respect to their production and ...
DMDS Bandara, S Premaratne, CMB Dematawewa   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Updating a Quality Management System for a Mexican Industrial Organization: Case Study

Businesses
The need to update an enterprise quality management system (QMS) seems to be more urgent each time. Without adequate updating, the system may not be capable of responding to market changes, generating delivery delays and increasing customer costs and ...
Julio César López-Figueroa, Ernesto A. Lagarda-Leyva, René Daniel Fornés-Rivera, Alfredo Bueno-Solano   +3 more
doaj   +1 more source