Results 41 to 50 of about 802,427 (265)

Improving the Dispersion Behavior of Organic Components in Water-Based Electrode Dispersions for Inkjet Printing Processes

open access: yesApplied Sciences, 2021
Water-based processing of electrodes is associated with an enhanced environmental footprint for lithium-ion battery (LIB) production in conjunction with reduced costs.
Cara G. Kolb   +4 more
doaj   +1 more source

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano   +7 more
wiley   +1 more source

Enhancing product design for remanufacturing: guidelines and their implementation in integrated remanufacturing systems

open access: yesProduction and Manufacturing Research: An Open Access Journal
Due to unsuitable design decisions, manufactured products are often unable to be remanufactured at the end of their lifetimes. This publication provides comprehensive guidelines for the design of products to facilitate remanufacturing across its various ...
Magdalena Paul   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Analysis of Contact Wheel and Tool Interaction in Belt Grinding

open access: yesJournal of Machine Engineering
The belt grinding process is gaining an increasing importance in the industrial sector. Due to its high flexibility regarding the range of workpiece materials and its adaptability to various, even geometrically complex workpiece shapes and designs, belt ...
Julian Wolfgang Henning   +2 more
doaj   +1 more source

Holistic Approach for an Energy-Flexible Operation of a Machine Tool with Cooling Supply

open access: yesEnergies, 2023
The following paper examines the practicality of a methodical approach for energy-flexible and energy-optimal operation in the field of metal-cutting production.
Martin Lindner   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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