Results 221 to 230 of about 2,594,206 (301)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

MIGS: A Modular Edge Gateway with Instance-Based Isolation for Heterogeneous Industrial IoT Interoperability. [PDF]

Sensors (Basel)
Ai Y, Zhu Y, Jiang Y, Deng Y.
europepmc   +1 more source

Managing without management

, 1997
openaire   +2 more sources

Excluded by design: a qualitative study of inequalities in health and social care innovation. [PDF]

Int J Equity Health
Tooman TR, Frost H, Adams R, Anand A, Aujla N, Bareham B, Guthrie B, Hanratty B, Kaner E, O'Donnell A, Ogden ME, Pain HG, Shenkin SD, Mercer SW.   +13 more
europepmc   +1 more source

Supporting the professional development of trial managers: how can you help? [PDF]

Trials
Mitchell EJ, Arundel C, Babalis D, Connolly S, Constable L, Goodman K, Stylianou L, Taylor J, Wakefield N, Williams S, Wolstenhulme F.   +10 more
europepmc   +1 more source

Stepped rehabilitation of people with persistent shoulder pain in New Zealand (StePS-NZ): a randomised clinical trial protocol. [PDF]

Trials
Sole G, Olds M, Bell R, Douglas C, Samaranayaka A, Sullivan T, Roy JS, Desmeules F, Swain N.   +8 more
europepmc   +1 more source