Results 131 to 140 of about 491,531 (328)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec   +5 more
wiley   +1 more source

Pension Fund Performance and Costs: Small is Beautiful [PDF]

open access: yes
Using the CEM pension fund data set, we document the cost structure and performance of a large sample of US pension funds. To date, self-reporting biases and a deficiency of comprehensive return and cost data have severely hindered pension fund ...
Bauer, R.M.M.J.   +2 more
core   +1 more source

From Statehouse to Schoolhouse: Anti-Bullying Policy Efforts in U.S. States and School Districts [PDF]

open access: yes, 2015
In 2011, 29.5 percent of U.S. public school districts didn't have anti-bullying policies, including many districts in states that require them, according to a report published by GLSEN.
Emily A. Greytak   +2 more
core  

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu   +10 more
wiley   +1 more source

Secrets of Your Leadership Success: The 11 Indispensable E’s of a Leader [PDF]

open access: yes, 2012
Professor Rao has used his experiences in organizational systems to produce a “recipe” for true leadership. In developing the 11 E’s — from Enthusiasm to Ethics —this author attempts to identify the traits characteristically and uniformly found in great ...
Rao, M. S
core   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

open access: yesAdvanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani   +7 more
wiley   +1 more source

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